Shinichiro Ohshimo 研究室

主宰者：Shinichiro Ohshimo

広島大学・Hiroshima University Hospital

AI 要約（直近 5 年の研究成果）

本研究室は、急性期医療において患者の予後を左右する重大な臨床問題を解明することに取り組んでいます。心停止患者の蘇生、急性呼吸促迫症候群や敗血症などの重症患者管理、および自然災害が健康に及ぼす影響といった多様な領域を対象としています。これらの課題に対し、全国の医療機関から収集した大規模なデータベースや臨床レジストリを活用した系統的な分析を主要な研究手法としています。具体的には、患者を危険度や臨床的特徴に基づいて層別化し、どのような治療や介入が特定の患者群で有効であるかを検証する研究が多くを占めます。例えば、心停止患者における蘇生継続の判断基準の開発、重症患者の人工呼吸離脱予測、早期リハビリテーションによる長期予後への影響などが検討されています。また、医療スタッフの配置変更や医療施設の負荷が患者転帰に与える影響といった、臨床現場の実情を反映した研究も進めています。さらに本研究室は、従来の臨床知見では説明しきれない患者集団の多様性に注目し、統計的手法を用いた患者の亜型分類や予測モデルの構築を行っています。これらの研究を通じて、より精密で個別化された医療の実現に貢献することを目指しています。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

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研究成果（85 件）

[2025] Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disease-19
DOI: https://doi.org/10.1186/s40560-025-00777-z
[2025] Changes in the neurological status from 30 to 90 days post-cardiac arrest by age: A nationwide retrospective observational study
DOI: https://doi.org/10.1016/j.resplu.2025.100917
[2025] Early Rehabilitation Interventions by Physical Therapists for Severe COVID-19 Patients Were Associated With Decreased Incidence of Post-ICU Physical Impairment
DOI: https://doi.org/10.5535/arm.240066
[2025] P aO 2 /F IO 2 -Based Stratification Discriminates Treatment Failure in Nonintubated Subjects With ARDS
DOI: https://doi.org/10.1177/19433654251376289
[2025] Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM–OHCA registry)
DOI: https://doi.org/10.1016/j.resuscitation.2024.110487
[2025] Association between hospital arrival time/day and mortality in pediatric patients with severe trauma: a nationwide retrospective observational study in Japan
DOI: https://doi.org/10.1016/j.injury.2025.112946
[2025] Development and validation of the STeP score for predicting tracheostomy in patients with sepsis using a nationwide ICU database: a retrospective observational study
DOI: https://doi.org/10.1186/s40560-025-00833-8
[2025] Abstract Sat1304: A Predictive Score for In-Transit Cardiac Arrest in Trauma Patients: Development and Validation Using a National Registry
DOI: https://doi.org/10.1161/circ.152.suppl_3.sat1304
[2025] Abstract Sat701: Prolonged In-Hospital CPR in Pediatric OHCA Patients with Estimated Poor Neurological Prognosis: Challenges in Termination Resuscitation in Children
DOI: https://doi.org/10.1161/circ.152.suppl_3.sat701
[2025] Impact of prefecture-level intensive care unit congestion on mortality in severe COVID-19 patients: a retrospective observational study in Japan
DOI: https://doi.org/10.1186/s12879-025-11755-z

続きを表示（残り 75 件）

[2025] Impact of staff turnover on extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a nationwide registry-based analysis in Japan
DOI: https://doi.org/10.1016/j.resplu.2025.101107
[2025] Increased antidepressant prescriptions following the 2018 Japan floods: a longitudinal analysis using the national health insurance database
DOI: https://doi.org/10.1080/20008066.2025.2537547
[2025] Exogenous Lipoid Pneumonia Induced by the Excessive Use of Menthol-containing Nasal Inhalers and Subsequent Acute Hypersensitivity Pneumonia Triggered by Domestic Environmental Antigens
DOI: https://doi.org/10.2169/internalmedicine.5358-25
[2025] Impact of 2018 Japan floods on allergic rhinitis prescriptions
DOI: https://doi.org/10.1016/j.waojou.2025.101051
[2025] Cross-sectional pilot study of relationships between specific oral bacteria and acute respiratory failure requiring intensive care unit admission
DOI: https://doi.org/10.1016/j.jdent.2025.105724
[2025] Serum Soluble Toll-Like Receptor 4 is a Predictive Biomarker for Acute Exacerbation and Prognosis of Idiopathic Pulmonary Fibrosis: A Retrospective Study
DOI: https://doi.org/10.1007/s00408-025-00800-y
[2025] Development of a Pharyngeal Residue Level Assessment Index Using Artificial Intelligence (AI) Acoustic Analysis: A Study Protocol
DOI: https://doi.org/10.7759/cureus.78358
[2024] Hypercalcemic Crisis Complicated With Acute Respiratory Distress Syndrome Due to Hot Spring Drowning: A Case Report
DOI: https://doi.org/10.7759/cureus.58431
[2024] Identification of novel sub-phenotypes of severe ARDS requiring ECMO using latent class analysis
DOI: https://doi.org/10.1186/s13054-024-05143-3
[2024] Tranexamic Acid in Pediatric Traumatic Brain Injury: A Multicenter Retrospective Observational Study
DOI: https://doi.org/10.1016/j.annemergmed.2024.07.014
[2024] Resuscitation Attempt and Outcomes in Patients With Asystole Out-of-Hospital Cardiac Arrest
DOI: https://doi.org/10.1001/jamanetworkopen.2024.45543
[2024] Serum soluble isoform of receptor for advanced glycation end product is a predictive biomarker for acute exacerbation of idiopathic pulmonary fibrosis: a German and Japanese cohort study
DOI: https://doi.org/10.1186/s12931-024-03014-7
[2024] Effect Size of Targeted Temperature Management in Pediatric Patients with Post-Cardiac Arrest Syndrome According to the Severity
DOI: https://doi.org/10.3390/life15010026
[2024] Dental Suction Interference and Acoustic Respiratory Monitoring
DOI: https://doi.org/10.2344/23-00017
[2024] Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study
DOI: https://doi.org/10.1186/s40560-024-00758-8
[2024] Diagnostic utility of plasma translocator protein 18 kDa (TSPO) in sepsis: A case–control study
DOI: https://doi.org/10.1097/md.0000000000040396
[2024] Characteristics of Bleeding Complications in Patients with Severe COVID-19 Requiring Veno-venous Extracorporeal Membrane Oxygenation in Japan
DOI: https://doi.org/10.1055/a-2411-1000
[2024] Rate of Asthma Prescriptions for Children and Adolescents During the 2018 Floods in Japan
DOI: https://doi.org/10.1542/peds.2023-065381
[2024] The Usefulness of Continuous Respiratory Sound Monitoring for the Detection of Pulmonary Atelectasis in a Ventilated Extremely Low Birth Weight Infant
DOI: https://doi.org/10.7759/cureus.65394
[2024] Pulmonary function and chest CT abnormalities 3 months after discharge from COVID-19, 2020–2021: A nation-wide multicenter prospective cohort study from the Japanese respiratory society
DOI: https://doi.org/10.1016/j.resinv.2024.02.009
[2024] Identifying Subgroups with Differential Responses to Amiodarone among Cardiac Arrest Patients with a Shockable Rhythm at Hospital Arrival using the Machine Learning Approach
DOI: https://doi.org/10.31083/j.rcm2507268
[2024] Lipocalin-2 as a prognostic marker in patients with acute exacerbation of idiopathic pulmonary fibrosis
DOI: https://doi.org/10.1186/s12931-024-02825-y
[2024] Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
DOI: https://doi.org/10.1016/j.heliyon.2024.e29591
[2024] Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry
DOI: https://doi.org/10.1186/s40560-023-00715-x
[2024] Face-to-face versus 360° VR video: a comparative study of two teaching methods in nursing education
DOI: https://doi.org/10.1186/s12912-024-01866-4
[2024] Differences in Pathophysiology and Treatment Efficacy Based on Heterogeneous Out-of-Hospital Cardiac Arrest
DOI: https://doi.org/10.3390/medicina60030510
[2024] External validation of the rCAST for patients after in-hospital cardiac arrest: a multicenter retrospective observational study
DOI: https://doi.org/10.1038/s41598-024-54851-x
[2024] High S100A9 level predicts poor survival, and the S100A9 inhibitor paquinimod is a candidate for treating idiopathic pulmonary fibrosis
DOI: https://doi.org/10.1136/bmjresp-2023-001803
[2024] External validation of the <scp>sICOP</scp> score for early mortality in mechanically ventilated patients with <scp>COVID</scp>‐19
DOI: https://doi.org/10.1002/ams2.978
[2023] Fulminant myocarditis proven by early biopsy and outcomes
DOI: https://doi.org/10.1093/eurheartj/ehad707
[2023] Predictive Accuracy of the ROX Index for Re-Intubation in Mechanically Ventilated Patients With COVID-19
DOI: https://doi.org/10.4187/respcare.10549
[2023] New acoustic monitoring system quantifying aspiration risk during monitored anaesthesia care
DOI: https://doi.org/10.1038/s41598-023-46561-7
[2023] Mechanical ventilation practices in Asian intensive care units: A multicenter cross-sectional study
DOI: https://doi.org/10.1016/j.jcrc.2023.154452
[2023] Abstract 147: Is Effect Size of Targeted Temperature Management Different for Pediatric Post-Cardiac Arrest Syndrome According to the Severity?
DOI: https://doi.org/10.1161/circ.148.suppl_1.147
[2023] Abstract 396: A Novel Machine Learning Approach for Identifying Subgroups With Differential Responses to Amiodarone in Patients With Cardiac Arrest With Shockable Rhythm
DOI: https://doi.org/10.1161/circ.148.suppl_1.396
[2023] Abstract 157: Differences in Mid-Term Neurological Changes From 30 to 90 Days According to Age; is Plasticity Following Brain Injury After Cardiac Arrest Observed in Children or Young Adults?
DOI: https://doi.org/10.1161/circ.148.suppl_1.157
[2023] Abstract 237: Effect of Hospital Arrival Time on Mortality Rate in Pediatric Patients With Severe Trauma: A Nationwide Database Study in Japan
DOI: https://doi.org/10.1161/circ.148.suppl_1.237
[2023] A Successful Prevention of Reintubation Using the Mechanical Insufflation-Exsufflation in a Critically Ill Patient With Impaired Airway Mucus Expectoration: A Case Report
DOI: https://doi.org/10.7759/cureus.47776
[2023] Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST
DOI: https://doi.org/10.1016/j.ajem.2023.10.028
[2023] Usefulness of Quantification and Serial Monitoring of Fine Crackles for Early Detection of Treatment-related Lung Injury: A Report of Two Cases
DOI: https://doi.org/10.2169/internalmedicine.2387-23
[2023] Characteristics of the pulmonary opacities on chest CT associated with difficulty in short-term liberation from veno-venous ECMO in patients with severe ARDS
DOI: https://doi.org/10.1186/s12931-023-02425-2
[2023] High versus low positive end-expiratory pressure setting in patients receiving veno-venous extracorporeal membrane oxygenation support for severe acute respiratory distress syndrome: study protocol for the multicentre, randomised ExPress SAVER Trial
DOI: https://doi.org/10.1136/bmjopen-2023-072680
[2023] Liver injury in hospitalized patients with COVID-19: An International observational cohort study
DOI: https://doi.org/10.1371/journal.pone.0277859
[2023] Continuous positive airway pressure versus high‐flow nasal cannula oxygen therapy for acute hypoxemic respiratory failure: A randomized controlled trial
DOI: https://doi.org/10.1111/resp.14588
[2023] Relationship between critical care nutrition and post-intensive care syndrome in surviving ventilated patients with COVID-19: a multicenter prospective observational study
DOI: https://doi.org/10.3164/jcbn.23-66
[2023] Multisystem inflammatory syndrome in adults with <scp>COVID</scp>‐19 requiring mechanical ventilation: A retrospective cohort study
DOI: https://doi.org/10.1002/ams2.885
[2023] Usefulness of new acoustic respiratory sound monitoring with artificial intelligence for upper airway assessment in obese patients during monitored anesthesia care
DOI: https://doi.org/10.2152/jmi.70.430
[2023] Temperature management using an intervascular cooling device for a <scp>COVID</scp> ‐19 patient with refractory hyperthermia
DOI: https://doi.org/10.1002/ccr3.7138
[2023] Lung Abscess and Pyothorax in Critically Ill COVID-19 Patients: A Single-Center Retrospective Study
DOI: https://doi.org/10.1097/cce.0000000000000919
[2022] Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study
DOI: https://doi.org/10.1186/s13054-021-03853-6
[2022] Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study
DOI: https://doi.org/10.1007/s10877-022-00884-4
[2022] Alarming of Severe Respiratory Failure Requiring ECMO Caused by the SARS-CoV-2 Omicron Variant
DOI: https://doi.org/10.31662/jmaj.2022-0049
[2022] External Validation of the sICOP Score for Early Mortality in Mechanically Ventilated Patients with COVID-19
DOI: https://doi.org/10.2139/ssrn.4308579
[2022] Trial of quantify for swallowing strength using an electronic stethoscope (An interim Report)
DOI: https://doi.org/10.7144/sgf.28.86
[2022] Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out‐of‐Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry
DOI: https://doi.org/10.1161/jaha.121.025048
[2022] Obesity and severe COVID-19: What are the pitfalls in ECMO?
DOI: https://doi.org/10.3918/jsicm.29_163
[2022] Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data
DOI: https://doi.org/10.1186/s13054-022-04187-7
[2022] Relation between nutrition therapy in the acute phase and outcomes of ventilated patients with COVID-19 infection: a multicenter prospective observational study
DOI: https://doi.org/10.1093/ajcn/nqac014
[2022] Prevalence and Risk Factor Analysis of Post-Intensive Care Syndrome in Patients with COVID-19 Requiring Mechanical Ventilation: A Multicenter Prospective Observational Study
DOI: https://doi.org/10.3390/jcm11195758
[2022] Neutralizing Type I Interferon Autoantibodies in Japanese Patients with Severe COVID-19
DOI: https://doi.org/10.1007/s10875-022-01308-3
[2022] Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report
DOI: https://doi.org/10.1007/s10877-022-00824-2
[2022] GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL
DOI: https://doi.org/10.1097/shk.0000000000002030
[2022] Prediction model for patient prognosis in idiopathic pulmonary fibrosis using hybrid radiomics analysis
DOI: https://doi.org/10.1016/j.redii.2022.100017
[2022] Real‐time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system
DOI: https://doi.org/10.1002/cre2.531
[2021] Pulmonary Alveolar Proteinosis with Severe Respiratory Failure Improved by Segmental Lung Lavage with Fiberoptic Bronchoscopy under General Anesthesia
DOI: https://doi.org/10.2169/internalmedicine.7432-21
[2021] A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study
DOI: https://doi.org/10.1007/s10877-020-00641-5
[2021] The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J‐SSCG 2020)
DOI: https://doi.org/10.1002/ams2.659
[2021] Prognostic Significance of EGFR Gene Mutation in Patients With EGFR Mutated Non-small Cell Lung Cancer Who Received Best Supportive Care Alone
DOI: https://doi.org/10.21873/anticanres.15047
[2021] A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia
DOI: https://doi.org/10.1097/md.0000000000024738
[2021] Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension
DOI: https://doi.org/10.1161/circ.144.suppl_1.10482
[2021] P1‐55: Pulmonary function after nintedanib treatment in post‐COVID‐19 pulmonary fibrosis
DOI: https://doi.org/10.1111/resp.14150_55
[2021] Potential clinical utility of MUC5B und TOLLIP single nucleotide polymorphisms (SNPs) in the management of patients with IPF
DOI: https://doi.org/10.1186/s13023-021-01750-3
[2021] Epidemiology and Outcomes of Critically Ill Children at Risk for Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study*
DOI: https://doi.org/10.1097/ccm.0000000000005287
[2021] Establishment of a Disaster Management-like System for COVID-19 Patients Requiring Veno-Venous Extracorporeal Membrane Oxygenation in Japan
DOI: https://doi.org/10.3390/membranes11080625
[2021] IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis
DOI: https://doi.org/10.1371/journal.pone.0252594

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AI 要約（直近 5 年の研究成果）

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関連研究室(8 件)

研究成果（85 件）

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