Masami Sugihara 研究室

AI 要約（直近 5 年の研究成果）

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

研究成果（14 件）

• [2026] A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function
  DOI: https://doi.org/10.1111/bph.70459
• [2025] RyR1-mediated Ca ²⁺ -induced Ca ²⁺ release plays a negligible role in excitation–contraction coupling of normal skeletal muscle
  DOI: https://doi.org/10.1073/pnas.2500449122
• [2025] ERC/Mesothelin Is Associated with the Formation of Microvilli on the Mesothelium and Has Limited Functional Relevance Under Physiological Conditions
  DOI: https://doi.org/10.3390/ijms26094330
• [2024] Effects of a high-affinity and selective RyR2 inhibitor on Ca2+ signals in cardiomyocytes and arrhythmias in CPVT model mice
  DOI: https://doi.org/10.1016/j.bpj.2023.11.247
• [2024] Dizziness and unstable gait in the older adults are associated with vestibular hypofunction, muscle dysfunction and sleep disturbance: impact on prevention of accidental falls
  DOI: https://doi.org/10.1186/s12877-024-05620-y
• [2023] Effects of a novel RyR2 specific inhibitor on arrhythmias in catecholaminergic polymorphic ventricular tachycardia (CPVT) model mice
  DOI: https://doi.org/10.1254/jpssuppl.97.0_1-b-o03-1
• [2023] Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring
  DOI: https://doi.org/10.1124/molpharm.123.000720
• [2023] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity
  DOI: https://doi.org/10.1016/j.bpj.2022.11.1395
• [2023] Effects of voluntary exercise and administration of renin angiotensin inhibitor on cardiac function in inherited dilated cardiomyopathy model
  DOI: https://doi.org/10.1016/j.bpj.2022.11.833
• [2022] Evaluation of RyR2 inhibitors as anti-arrhythmic drugs using novel CPVT model mice
  DOI: https://doi.org/10.1254/jpssuppl.95.0_3-p-228

科研費（0 件）

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所属学会・役職（0 件）

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