Maki Hirata 研究室

主宰者：Maki Hirata

徳島大学

AI 要約（直近 5 年の研究成果）

要約はまだ生成されていません。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

外部リンク

研究成果（56 件）

[2026] Double Electroporation Combined with Zona Pellucida Removal Improves Biallelic Genome Editing Efficiency in Porcine Embryos
DOI: https://doi.org/10.3390/ani16121919
[2026] Selection of two pronuclei zygotes before electroporation does not improve gene editing efficiency or reduce mosaicism in porcine embryos despite optimized timing and Hoechst staining
DOI: https://doi.org/10.14202/vetworld.2026.2406-2417
[2026] Advances in gene editing strategies for viral disease resistance in pigs: Knock-out, knock-in, and overexpression approaches
DOI: https://doi.org/10.56808/2985-1130.3983
[2025] IL2RG deficient X-SCID pigs generated via electroporation-mediated gene editing using CRISPR/Cas9
DOI: https://doi.org/10.1093/jas/skaf350
[2025] Indole-3-propionic acid supplementation during in vitro maturation improves in vitro production of porcine embryos
DOI: https://doi.org/10.1186/s12917-025-05049-4
[2025] Establishment of a Single-Oocyte Culture System for Pigs and Its Validation Using Curcumin as a Model Antioxidant for Oocyte Maturation
DOI: https://doi.org/10.3390/ani15223295
[2025] Mitochondrial-Targeted Protective Potential of Elamipretide for the In Vitro Production of Porcine Embryos
DOI: https://doi.org/10.3390/ani15172497
[2025] Oxidative stress index of porcine follicular fluid influences meiotic maturation and embryo development during in vitro culture
DOI: https://doi.org/10.14202/vetworld.2025.2078-2086
[2025] Effects of Electroporation Timing and Cumulus Cell Attachment on In Vitro Development and Genome Editing of Porcine Embryos
DOI: https://doi.org/10.1111/rda.70011
[2025] Aberrant Expression Levels of Androgen Receptor and SRD5A2 in Epididymal Epithelial Cells of Crossbred Infertile Cattle–Yak
DOI: https://doi.org/10.3390/ani15050660

続きを表示（残り 46 件）

[2025] Zinc Chloride Supplementation During In Vitro Fertilization Reduces Polyspermic Fertilization of Porcine Oocytes
DOI: https://doi.org/10.1111/asj.70095
[2025] Relationship Between Methane Emissions and Intestinal Methanogenic Microbiota in Micro‐Mini Pigs
DOI: https://doi.org/10.1111/asj.70130
[2024] Generation of allogenic chimera carrying mutations in PDX1 and TP53 genes via phytohemagglutinin-mediated blastomere aggregation in pigs
DOI: https://doi.org/10.1007/s11626-024-00870-x
[2024] Efficient gene editing of pig embryos by combining electroporation and lipofection
DOI: https://doi.org/10.14202/vetworld.2024.2701-2707
[2024] Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
DOI: https://doi.org/10.1007/s11626-024-00987-z
[2024] Effects of ergothioneine supplementation on meiotic competence and porcine oocyte development
DOI: https://doi.org/10.14202/vetworld.2024.1748-1752
[2024] Effects of centrifugation treatment before electroporation on gene editing in pig embryos
DOI: https://doi.org/10.1007/s11626-024-00926-y
[2024] Evaluation of culture methods and chemical reagent combinations on CRISPR/Cas9 gene editing systems by lipofection in pig zygotes
DOI: https://doi.org/10.1007/s11626-024-00908-0
[2024] Programmed cell death-1-modified pig developed using electroporation-mediated gene editing for in vitro fertilized zygotes
DOI: https://doi.org/10.1007/s11626-024-00869-4
[2024] Genome editing of porcine zygotes via lipofection of two guide RNAs using a CRISPR/Cas9 system
DOI: https://doi.org/10.1262/jrd.2024-054
[2023] 156 Genome editing of porcine zygotes through the lipofection of a CRISPR/Cas9 system with two guide RNAs
DOI: https://doi.org/10.1071/rdv36n2ab156
[2023] Vitrified before and after genome editing via electroporation.
[2023] Evaluating variations in bilirubin glucuronidation activity by protease inhibitors in canine and human primary hepatocytes cultured in a 3D culture system
DOI: https://doi.org/10.1016/j.tiv.2023.105689
[2023] GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system
DOI: https://doi.org/10.1007/s11033-023-08388-3
[2023] Development and Genome Mutation of Bovine Zygotes Vitrified Before and After Genome Editing via Electroporation
DOI: https://doi.org/10.54680/fr23210110612
[2023] Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN
DOI: https://doi.org/10.3389/fcell.2023.884340
[2023] GEEP Method: An Optimized Electroporation-Mediated Gene Editing Approach for Establishment of Knockout Pig Lines
DOI: https://doi.org/10.1007/978-1-0716-3016-7_22
[2023] Comparison of chemically mediated CRISPR/Cas9 gene editing systems using different nonviral vectors in porcine embryos
DOI: https://doi.org/10.1111/asj.13878
[2023] Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study
DOI: https://doi.org/10.1155/2023/7000858
[2023] Efficiency of genetic modification in gene‐knockout sperm‐derived zygotes followed by electroporation of guide RNA targeting the same gene
DOI: https://doi.org/10.1111/asj.13842
[2022] Supplemental Clostridium butyricum MIYAIRI 588 Affects Intestinal Bacterial Composition of Finishing Pigs
[2022] Multiple gene editing in porcine embryos using a combination of microinjection, electroporation, and transfection methods
DOI: https://doi.org/10.14202/vetworld.2022.2210-2216
[2022] Comparative analysis of bilirubin glucuronidation activity in canine and human primary hepatocytes using a 3D culture system
DOI: https://doi.org/10.1007/s11626-022-00711-9
[2022] Gene editing in porcine embryos using a combination of electroporation and transfection methods
DOI: https://doi.org/10.1111/rda.14184
[2022] Disruption of cell proliferation and apoptosis balance in the testes of crossbred cattle‐yaks affects spermatogenic cell fate and sterility
DOI: https://doi.org/10.1111/rda.14166
[2022] Effects of the timing of electroporation during in vitro maturation on triple gene editing in porcine embryos using CRISPR/Cas9 system
DOI: https://doi.org/10.1016/j.vas.2022.100241
[2022] Triple gene editing in porcine embryos using electroporation alone or in combination with microinjection
DOI: https://doi.org/10.14202/vetworld.2022.496-501
[2022] Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature
DOI: https://doi.org/10.1111/rda.14095
[2022] Supplemental Clostridium butyricum MIYAIRI 588 Affects Intestinal Bacterial Composition of Finishing Pigs
DOI: https://doi.org/10.1264/jsme2.me22011
[2022] Short‐term preservation of porcine zygotes at ambient temperature using a chemically defined medium
DOI: https://doi.org/10.1111/asj.13711
[2021] Generation of mutant pigs by lipofection-mediated genome editing in embryos
DOI: https://doi.org/10.1038/s41598-021-03325-5
[2021] Effects of individual or in‐combination antioxidant supplementation during in vitro maturation culture on the developmental competence and quality of porcine embryos
DOI: https://doi.org/10.1111/rda.14063
[2021] Aberrant levels of DNA methylation and H3K9 acetylation in the testicular cells of crossbred cattle–yak showing infertility
DOI: https://doi.org/10.1111/rda.14061
[2021] Development and characterization of Gal KO porcine bone marrow‐derived mesenchymal stem cells
DOI: https://doi.org/10.1111/xen.12717
[2021] Zona pellucida treatment before CRISPR/Cas9‐mediated genome editing of porcine zygotes
DOI: https://doi.org/10.1002/vms3.659
[2021] Timing and duration of lipofection-mediated CRISPR/Cas9 delivery into porcine zygotes affect gene-editing events
DOI: https://doi.org/10.1186/s13104-021-05800-8
[2021] In vitro Development of Zona Pellucida-free Porcine Zygotes Cultured Individually after Vitrification.
[2021] Vaginal stimulation enhances ovulation of queen ovaries treated using a combination of eCG and hCG
DOI: https://doi.org/10.1002/vms3.552
[2021] Improvement of the in vitro fertilization and embryo development using frozen–thawed spermatozoa of microminipigs
DOI: https://doi.org/10.5194/aab-64-265-2021
[2021] Comparison of Blastocyst Development between Cat-Cow and Cat-Pig Interspecies Somatic Cell Nuclear Transfer Embryos Treated with Trichostatin A
DOI: https://doi.org/10.1134/s1062359021020035
[2021] One-Step Generation of Multiple Gene-Edited Pigs by Electroporation of the CRISPR/Cas9 System into Zygotes to Reduce Xenoantigen Biosynthesis
DOI: https://doi.org/10.3390/ijms22052249
[2021] Lipofection-Mediated Introduction of CRISPR/Cas9 System into Porcine Oocytes and Embryos
DOI: https://doi.org/10.3390/ani11020578
[2021] Comparison of the effects of introducing the CRISPR/Cas9 system by microinjection and electroporation into porcine embryos at different stages
DOI: https://doi.org/10.1186/s13104-020-05412-8
[2021] Introduction of a point mutation in the KRAS gene of in vitro fertilized porcine zygotes via electroporation of the CRISPR/Cas9 system with single‐stranded oligodeoxynucleotides
DOI: https://doi.org/10.1111/asj.13534
[2021] Lipofection-mediated introduction of CRISPR/Cas9 system into porcine zygotes
DOI: https://doi.org/10.14882/jrds.114.0_aw-9
[2021] Chlorogenic acid and insulin–transferrin–selenium supplementation during in vitro maturation enhances the developmental competence of interspecies chimera blastocysts following cell injection
DOI: https://doi.org/10.1080/09712119.2021.2011295

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AI 要約（直近 5 年の研究成果）

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関連研究室(8 件)

研究成果（56 件）

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