Zentaro Yamagata 研究室

主宰者：Zentaro Yamagata

山梨大学・University of Yamanashi Hospital

AI 要約（直近 5 年の研究成果）

本研究室は、大規模な出生コホート研究「日本環境と子どもの研究（JECS）」を中心に、妊娠期から幼少期にかけての環境要因と子どもの発育・発達の関連を明らかにする研究を行っています。特に、妊娠中の母親の生活習慣（食事、運動、喫煙など）、心身の状態（心理的ストレス、自閉症的特性など）、医学的背景（基礎疾患、薬剤使用など）が、出生結果や子どもの神経発達にどのような影響を及ぼすかを調査しています。手法としては、全国15地域の病院で登録された約8万組の母子ペアから、質問票調査、臨床検査（血液検査など）、遺伝子解析、生体計測などを組み合わせたデータを収集し、統計解析を用いて関連性を検証しています。一部の研究では遺伝的背景の個人差にも着目し、同じ環境暴露であっても遺伝子型によって子どもへの影響が異なることを検討しています。さらに、アレルギー疾患（食物アレルギー、皮膚感染症）、身体発育（体成分、身体活動能力）、消化器機能（便秘）、感染症罹患など、小児の多様な健康課題を対象にした研究も展開しており、環境因子と子どもの健康の包括的な理解を目指しています。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

外部リンク

研究成果（100 件）

[2025] Relationship of flatfoot to physical performance and postural stability in children: The Yamanashi adjunct study of the Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.gaitpost.2025.109992
[2025] Effects of outdoor play on body composition and physical performance in children: the Yamanashi Adjunct study of the Japan Environment and Children’s Study
DOI: https://doi.org/10.1371/journal.pone.0317925
[2025] Low glucose challenge test result as a potential risk factor for delays in early child development: the Japan environment and children’s study
DOI: https://doi.org/10.1007/s40200-025-01568-x
[2025] The association of environmental house dust mite allergens and crustacean allergy: The Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.5415/apallergy.0000000000000169
[2025] Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers
DOI: https://doi.org/10.1001/jamanetworkopen.2025.40907
[2024] Maternal alcohol consumption during pregnancy and child development: Role of <scp><i>ADH1B</i></scp> and <scp><i>ALDH2</i></scp> gene polymorphisms—The Yamanashi Adjunct Study of the Japan Environment and Children's Study
DOI: https://doi.org/10.1111/acer.15487
[2024] High barley intake in non-obese individuals is associated with high natto consumption and abundance of butyrate-producing bacteria in the gut: a cross-sectional study
DOI: https://doi.org/10.3389/fnut.2024.1434150
[2024] Genetic Variants Associated With a History of Glaucoma Surgery in Japanese Patients With Primary Open Angle Glaucoma
DOI: https://doi.org/10.1097/ijg.0000000000002510
[2024] Infants’ early recovery from sleep disturbance is associated with a lower risk of developmental delay in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-024-68672-5
[2024] Maternal excessive weight gain as a potential risk factor for prolonged labor in Japanese pregnant women: The Japan Environment and Children’s Study
DOI: https://doi.org/10.1371/journal.pone.0306247

続きを表示（残り 90 件）

[2024] Neonatal transfer and duration of hospitalization of newborns as potential risk factors for impaired mother-infant bonding: The Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.jad.2024.06.001
[2024] Abnormality in re-programing of preparatory muscle activity for landing following unpredictable events in patients with anterior cruciate ligament injury
DOI: https://doi.org/10.1016/j.knee.2024.05.004
[2024] Risk of Gestational Diabetes in Women With PCOS Based on Body Mass Index: The Japan Environment and Children's Study
DOI: https://doi.org/10.1210/clinem/dgae293
[2024] Prenatal risk factors of indoor environment and incidence of childhood eczema in the Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.envres.2024.118871
[2024] Continuous Support from the Same Public Health Nurse and Parental Perception and Use of Health Care Services: A Retrospective Observational Study
DOI: https://doi.org/10.1007/s10995-024-03971-x
[2024] Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1038/s41598-024-55623-3
[2024] Association between daily breakfast habit during pregnancy and neurodevelopment in 3-year-old offspring: The Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-024-55912-x
[2024] Hypertensive disorders of pregnancy increase the incidence of febrile seizures in offspring
DOI: https://doi.org/10.1038/s41390-024-03057-y
[2024] Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study
DOI: https://doi.org/10.1111/1346-8138.17157
[2024] Maternal Autistic Traits and Adverse Birth Outcomes
DOI: https://doi.org/10.1001/jamanetworkopen.2023.52809
[2024] Association of air purifier usage during pregnancy with adverse birth outcomes: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12889-024-20802-4
[2024] Transboundary air pollution in coastal urban area in Japan: Transport model and positive matrix factorization analysis for SPM-PM2.5 and PM2.5
DOI: https://doi.org/10.1016/j.uclim.2024.102237
[2024] Active social participation extends the healthy life expectancy of older men without spouses in Japan: The Yamanashi healthy active life expectancy cohort study
DOI: https://doi.org/10.1097/md.0000000000040755
[2023] A nationwide, prospective, cohort study on exogenous oxytocin and delays in early child development: the Japan environment and children’s study
DOI: https://doi.org/10.1007/s00431-023-05079-w
[2023] Association between maternal cholesterol level during pregnancy and placental weight and birthweight ratio: data from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-023-05810-3
[2023] Reference blood pressure values obtained using the auscultation method for 2-year-old Japanese children: from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1007/s10157-023-02370-w
[2023] Association of influenza vaccination or influenza virus infection history with subsequent infection risk among children: The Japan Environment and Children's Study (JECS)
DOI: https://doi.org/10.1016/j.ypmed.2023.107599
[2023] Association between Cesarean section and neurodevelopmental disorders in a Japanese birth cohort: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12887-023-04128-5
[2023] Sleep quality and temperament in association with autism spectrum disorder among infants in Japan
DOI: https://doi.org/10.1038/s43856-023-00314-9
[2023] Prenatal folic acid supplement/dietary folate and cognitive development in 4-year-old offspring from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-023-36484-8
[2023] Current situation of the hospitalization of persons without family in Japan and related medical challenges
DOI: https://doi.org/10.1371/journal.pone.0276090
[2023] Impact of Habitual Yogurt Intake in Mother–Child Dyads on Incidence of Childhood Otitis Media: The Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1007/s12602-023-10086-2
[2023] Characteristic Gut Bacteria in High Barley Consuming Japanese Individuals without Hypertension
DOI: https://doi.org/10.3390/microorganisms11051246
[2023] Interpregnancy weight change as a potential risk factor for large-for-gestational-age infants: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1080/14767058.2023.2209251
[2023] Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-023-33653-7
[2023] Multiple pregnancy as a potential risk factor for postpartum depression: The Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.jad.2023.02.088
[2023] Maternal smoking status before and during pregnancy and bronchial asthma at 3 years of age: a prospective cohort study
DOI: https://doi.org/10.1038/s41598-023-30304-9
[2023] ‘Caregivers' awareness matters’: Call for a child‐centred approach to early detection of autism spectrum disorder through well‐child visits in Japan
DOI: https://doi.org/10.1111/cch.13107
[2023] Season of birth and atopic dermatitis in early infancy: results from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12887-023-03878-6
[2023] Developing an obstetric care screening tool to improve social support access for pregnant women: A prospective cohort study
DOI: https://doi.org/10.3389/fgwh.2022.921361
[2023] Maternal protein intake in early pregnancy and child development at age 3 years
DOI: https://doi.org/10.1038/s41390-022-02435-8
[2023] Relationship between floating toes condition and lower limb muscle weight in 8-year-old children: the Yamanashi adjunct study of the Japan Environment and Children’s Study (JECS-Y)
DOI: https://doi.org/10.1589/jpts.35.252
[2023] Retrospective analysis on gestational weight gain in twin pregnancies with favorable perinatal outcomes: The Japan Environment and Children's Study (JECS)
DOI: https://doi.org/10.3418/jjam.jjam-2022-0043
[2023] Effect of birth season on allergic rhinitis and cedar pollinosis considering allergen and vitamin D exposure: The Japan Environment and Children's study (JECS)
DOI: https://doi.org/10.1016/j.alit.2023.01.003
[2023] Maternal Serum Folic Acid Levels and Onset of Kawasaki Disease in Offspring During Infancy
DOI: https://doi.org/10.1001/jamanetworkopen.2023.49942
[2023] Association of Preconception or Antepartum Maternal Intimate Partner Violence with Autism Spectrum Disorder in 3-Year-Old Offspring: The Japan Environment and Children's Study
DOI: https://doi.org/10.1089/jwh.2022.0439
[2023] Impact of dog and/or cat ownership on functional constipation at 3 years of age: the Japan Environment and Children’s study
DOI: https://doi.org/10.1186/s12887-023-04412-4
[2023] Teenage and young adult pregnancy and depression: findings from the Japan environment and children’s study
DOI: https://doi.org/10.1007/s00737-023-01400-6
[2023] Impact of breastfeeding during infancy on functional constipation at 3 years of age: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s13006-023-00592-y
[2023] Longitudinal study of the relationship between number of prior miscarriages or stillbirths and changes in quality of life of pregnant women: the Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1186/s12884-023-05578-6
[2023] Infantile Peanut Introduction and Peanut Allergy in Regions With a Low Prevalence of Peanut Allergy: The Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.2188/jea.je20230210
[2023] Antibiotic prescription for outpatients with influenza and subsequent hospitalisation: A cohort study using insurance data
DOI: https://doi.org/10.1111/irv.13221
[2023] Neurodevelopmental Outcomes Among Offspring Exposed to Corticosteroid and B2-Adrenergic Agonists In Utero
DOI: https://doi.org/10.1001/jamanetworkopen.2023.39347
[2023] Prenatal metal concentrations and physical abnormalities in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41390-023-02851-4
[2023] Prediction of gestational diabetes mellitus using machine learning from birth cohort data of the Japan Environment and Children's Study
DOI: https://doi.org/10.1038/s41598-023-44313-1
[2023] Tocolytic treatment and maternal characteristics, obstetric outcomes, and offspring childhood outcomes among births at and after 37 weeks of gestation: the Japan environment and children’s study
DOI: https://doi.org/10.1007/s00404-023-07203-5
[2023] Effect of nausea and vomiting during pregnancy on mother-to-infant bonding and the mediation effect of postpartum depression: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-023-06014-5
[2023] Screen Time and Developmental Performance Among Children at 1-3 Years of Age in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1001/jamapediatrics.2023.3643
[2023] Refractive Error and Axial Length and Their Related Factors in 8-Year-Old Japanese Children: The Yamanashi Adjunct Study of the Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.3390/jcm12185929
[2023] Mother–child correlation of kidney function: data from the Yamanashi Adjunct Study of Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1007/s00467-023-06131-5
[2023] Obesity as a potential risk factor for stillbirth: The Japan Environment and Children’s Study
DOI: https://doi.org/10.1016/j.pmedr.2023.102391
[2023] Environments affect blood pressure in toddlers: The Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41390-023-02796-8
[2023] Association between gestational age at threatened preterm birth diagnosis and incidence of preterm birth: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-023-38524-9
[2023] Cord blood triglyceride and total cholesterol in preterm and term neonates: reference values and associated factors from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1007/s00431-023-05118-6
[2023] Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study
DOI: https://doi.org/10.3389/fnut.2023.1203669
[2023] Paternal involvement in infant care and developmental milestone outcomes at age 3 years: the Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1038/s41390-023-02723-x
[2022] Appropriate procedures to increase the adherence of children to blood collection: A cross‐sectional study
DOI: https://doi.org/10.1002/hsr2.1036
[2022] Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-022-26748-0
[2022] [Digitization and utilization of data on maternal and child health services in municipalities: Current status and issues].
DOI: https://doi.org/10.11236/jph.22-027
[2022] Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-022-24359-3
[2022] Genetic variants associated with glaucomatous visual field loss in primary open-angle glaucoma
DOI: https://doi.org/10.1038/s41598-022-24915-x
[2022] Exposure to House Dust Mite Allergen and Endotoxin in Early Life and Sensitization and Allergic Rhinitis: The JECS
DOI: https://doi.org/10.3390/ijerph192214796
[2022] Factor structure of the Parenting Stress Index-Short Form used in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-022-23849-8
[2022] Maternal hemoglobin levels and neonatal outcomes: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1080/14767058.2022.2130237
[2022] Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening
DOI: https://doi.org/10.3389/fragi.2022.965199
[2022] No association between prenatal lead exposure and neurodevelopment during early childhood in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1038/s41598-022-19509-6
[2022] Association between the ratio of placental weight to birthweight and the risk of neurodevelopmental delay in 3-year-Olds: The Japan environment and Children's study
DOI: https://doi.org/10.1016/j.placenta.2022.08.007
[2022] The association between early formula and reduced risk of cow’s milk allergy during the first three year of life: a Japanese cohort study
DOI: https://doi.org/10.1186/s13223-022-00712-z
[2022] Association between maternal fermented food consumption and child sleep duration at the age of 3 years: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12889-022-13805-6
[2022] Gestational weight gain mediates the effects of energy intake on birth weight among singleton pregnancies in the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-022-04898-3
[2022] Preconception vitamin D intake and obstetric outcomes in women using assisted reproductive technology: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-022-04861-2
[2022] Gestational age, birth weight, and perinatal complications in mothers with diabetes and impaired glucose tolerance: Japan Environment and Children’s Study cohort
DOI: https://doi.org/10.1371/journal.pone.0269610
[2022] Screen Timing May Be More Likely Than Screen Time to Be Associated With the Risk of Autism Spectrum Disorder—Reply
DOI: https://doi.org/10.1001/jamapediatrics.2022.1513
[2022] Association of the incidence of atopic dermatitis until 3 years old with climate conditions in the first 6 months of life: Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1371/journal.pone.0268204
[2022] Social isolation among mothers caring for Infants in Japan: findings from the Nationwide Survey of healthy parents and children 21
DOI: https://doi.org/10.1007/s10995-022-03427-0
[2022] Maternal Chronic Disease and Congenital Anomalies of the Kidney and Urinary Tract in Offspring: A Japanese Cohort Study
DOI: https://doi.org/10.1053/j.ajkd.2022.03.003
[2022] Maternal Urinary Cotinine Concentrations During Pregnancy Predict Infant BMI Trajectory After Birth: Analysis of 89617 Mother-Infant Pairs in the Japan Environment and Children’s Study
DOI: https://doi.org/10.3389/fendo.2022.850784
[2022] Association of physical activity and sleep habits during pregnancy with autistic spectrum disorder in 3-year-old infants
DOI: https://doi.org/10.1038/s43856-022-00101-y
[2022] Association between maternal gestational diabetes mellitus and high‐sensitivity C‐reactive protein levels in 8‐year‐old children: The Yamanashi Adjunct Study of the Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.1111/jdi.13796
[2022] Prenatal occupational disinfectant exposure and childhood allergies: the Japan Environment and Children’s study
DOI: https://doi.org/10.1136/oemed-2021-108034
[2022] Long-term outcomes of children with neonatal transfer: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1007/s00431-022-04450-7
[2022] Classification of the Occurrence of Dyslipidemia Based on Gut Bacteria Related to Barley Intake
DOI: https://doi.org/10.3389/fnut.2022.812469
[2022] Relationships between barley consumption and gut microbiome characteristics in a healthy Japanese population: a cross-sectional study
DOI: https://doi.org/10.1186/s40795-022-00500-3
[2022] Lack of catch-up in weight gain may intermediate between pregnancies with hyperemesis gravidarum and reduced fetal growth: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-022-04542-0
[2022] Maternal BMI and allergy in children until 3 years of age (JECS)
DOI: https://doi.org/10.1016/j.jacig.2022.02.003
[2022] Human Fetal Tissue Research and Research Ethics Guidelines
DOI: https://doi.org/10.4091/iken.2022.001
[2022] A cross-sectional study on the correlations between floating toe, plantar arch posture, and body composition in 8-year-old children
DOI: https://doi.org/10.1016/j.fas.2022.02.011
[2022] Severity of low pre-pregnancy body mass index and perinatal outcomes: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s12884-022-04418-3
[2022] High Incidence of Atopic Dermatitis among Children Whose Fathers Work in Primary Industry: The Japan Environment and Children’s Study (JECS)
DOI: https://doi.org/10.3390/ijerph19031761
[2022] Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age
DOI: https://doi.org/10.1001/jamapediatrics.2021.5778

科研費（0 件）

まだデータがありません（KAKEN 取り込み後に表示）。

所属学会・役職（0 件）

まだデータがありません（学会データ連携後に表示）。

AI 要約（直近 5 年の研究成果）

外部リンク

関連研究室(8 件)

研究成果（100 件）

科研費（0 件）

所属学会・役職（0 件）