Masateru Takigawa 研究室
主宰者:Masateru Takigawa
東京大学・University of Tokyo Hospital
兼任:東京医科歯科大学
AI 要約(直近 5 年の研究成果)
滝川雅輝研究室では、心臓のリズム異常、特に心房細動などの不整脈に対する治療法の開発と改善に取り組んでいます。研究の主な関心は、カテーテルを用いた焼灼術や新しい高周波治療技術を通じて、不整脈の患部をより正確に特定し、安全かつ効果的に治療することです。また、人工知能や機械学習を活用して、心電図や電気的な信号から不整脈の発症リスクを予測したり、治療時の焼灼範囲を最適化したりする研究も進めています。
手法としては、動物実験と臨床研究の両面から検証を行っています。基礎研究では豚などの動物モデルを用いた ex vivo および in vivo での焼灼実験を実施し、治療パラメータと組織傷害の関係を詳細に分析しています。臨床研究では、実際の患者から得られたデータを大規模に収集・分析し、治療安全性の監視や実臨床での応用可能性を評価しています。さらに、心房からの組織採取や心臓内超音波ガイド下の診断手技の安全性確立にも力を入れています。
これらの研究を通じて、焼灼時の電気インピーダンスの変化パターンの解釈、異なる出力設定での最適な治療深度の実現、治療後合併症の予防と対応など、不整脈治療の精度と安全性を段階的に向上させる知見を生み出しています。同時に、患者の遺伝的背景や血液マーカーを組み込んだリスク予測システムの開発により、より個別化された予防・治療戦略の構築に貢献しています。
※ AI(Claude)が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。
外部リンク
関連研究室(8 件)
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研究成果(191 件)
- DOI: https://doi.org/10.1111/pace.70208
- [2026] Accurate estimation of lesion metrics in radiofrequency ablation using machine learning modelDOI: https://doi.org/10.1093/ehjopen/oeag013
- DOI: https://doi.org/10.1016/j.hrthm.2026.03.1166
- DOI: https://doi.org/10.1016/j.hrthm.2026.03.1945
- DOI: https://doi.org/10.1016/j.hrthm.2026.03.1951
- DOI: https://doi.org/10.1016/j.jacasi.2025.10.009
- DOI: https://doi.org/10.1016/j.jccase.2026.01.014
- DOI: https://doi.org/10.1016/j.hrthm.2026.03.489
- DOI: https://doi.org/10.1111/jce.70284
- DOI: https://doi.org/10.1093/europace/euag026
続きを表示(残り 181 件)閉じる
- DOI: https://doi.org/10.1016/j.hrcr.2026.01.006
- [2026] Accurate estimation of lesion metrics in radiofrequency ablation using machine learning modelDOI: https://doi.org/10.1093/ehjopen/oeag013
- DOI: https://doi.org/10.1016/j.hrthm.2026.05.028
- DOI: https://doi.org/10.1093/eurheartj/ehag486
- DOI: https://doi.org/10.1161/circep.125.014823
- DOI: https://doi.org/10.1007/s10840-025-02106-8
- DOI: https://doi.org/10.1253/circrep.cr-25-0101
- DOI: https://doi.org/10.1093/europace/euaf135
- DOI: https://doi.org/10.1016/j.hrthm.2025.05.072
- DOI: https://doi.org/10.1111/pace.15195
- [2025] PO-FP-010 DISCRIMINATING VIABLE TISSUE FROM TRUE SCAR USING PEAK FREQUENCY AND OMNIPOLAR VOLTAGEDOI: https://doi.org/10.1016/j.hrthm.2025.03.177
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1195
- DOI: https://doi.org/10.1371/journal.pone.0321604
- DOI: https://doi.org/10.1007/s10840-025-02106-8
- DOI: https://doi.org/10.1253/circrep.cr-25-0101
- DOI: https://doi.org/10.1093/europace/euaf135
- DOI: https://doi.org/10.1016/j.hrthm.2025.05.072
- DOI: https://doi.org/10.1111/pace.15195
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1195
- DOI: https://doi.org/10.1111/jce.16675
- [2025] PO-FP-010 DISCRIMINATING VIABLE TISSUE FROM TRUE SCAR USING PEAK FREQUENCY AND OMNIPOLAR VOLTAGEDOI: https://doi.org/10.1016/j.hrthm.2025.03.177
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1221
- [2025] PO-04-094 EFFECT OF PULSED FIELD ABLATION WITH A VARIABLE LOOP CATHETER ON CARDIAC DEVICE SYSTEMDOI: https://doi.org/10.1016/j.hrthm.2025.03.1228
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1185
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1189
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1637
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1116
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.420
- DOI: https://doi.org/10.1016/j.jccase.2025.01.003
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.420
- DOI: https://doi.org/10.1093/europace/euaf324
- [2025] Averaging real-time impedance enhances the prediction of steam pop risk and lesion characteristicsDOI: https://doi.org/10.1093/europace/euaf315
- DOI: https://doi.org/10.1002/joa3.70250
- DOI: https://doi.org/10.1093/ehjcr/ytaf581
- DOI: https://doi.org/10.1093/eurheartj/ehaf784.473
- DOI: https://doi.org/10.1111/jce.70125
- [2025] Averaging real-time impedance enhances the prediction of steam pop risk and lesion characteristicsDOI: https://doi.org/10.1093/europace/euaf315
- DOI: https://doi.org/10.1002/joa3.70250
- DOI: https://doi.org/10.1093/ehjcr/ytaf581
- DOI: https://doi.org/10.1111/jce.70125
- DOI: https://doi.org/10.1016/j.jacep.2025.07.029
- DOI: https://doi.org/10.1016/j.hrthm.2025.09.015
- DOI: https://doi.org/10.1111/jce.16675
- DOI: https://doi.org/10.1371/journal.pone.0321604
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1221
- [2025] PO-04-094 EFFECT OF PULSED FIELD ABLATION WITH A VARIABLE LOOP CATHETER ON CARDIAC DEVICE SYSTEMDOI: https://doi.org/10.1016/j.hrthm.2025.03.1228
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1185
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1189
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1637
- DOI: https://doi.org/10.1016/j.hrthm.2025.03.1116
- DOI: https://doi.org/10.1016/j.jccase.2025.01.003
- DOI: https://doi.org/10.1002/joa3.13182
- DOI: https://doi.org/10.1016/j.jacep.2025.07.029
- DOI: https://doi.org/10.1016/j.hrthm.2025.09.015
- DOI: https://doi.org/10.1002/joa3.13182
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.002
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.416
- DOI: https://doi.org/10.1111/jce.16514
- DOI: https://doi.org/10.1111/jce.16516
- DOI: https://doi.org/10.1111/jce.16453
- DOI: https://doi.org/10.1016/j.jacc.2024.08.060
- DOI: https://doi.org/10.1016/j.hrthm.2024.10.026
- DOI: https://doi.org/10.1002/joa3.12992
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.002
- DOI: https://doi.org/10.1111/jce.16514
- DOI: https://doi.org/10.1111/jce.16516
- DOI: https://doi.org/10.1111/jce.16453
- DOI: https://doi.org/10.1016/j.jacc.2024.08.060
- DOI: https://doi.org/10.1016/j.hrthm.2024.10.026
- DOI: https://doi.org/10.1093/eurheartj/ehae666.400
- DOI: https://doi.org/10.1002/joa3.13040
- DOI: https://doi.org/10.1093/eurheartj/ehae666.400
- DOI: https://doi.org/10.1007/s10840-024-01912-w
- DOI: https://doi.org/10.1111/jce.16408
- DOI: https://doi.org/10.1111/jce.16415
- DOI: https://doi.org/10.1007/s10840-024-01845-4
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.1374
- DOI: https://doi.org/10.1007/s10840-024-01912-w
- DOI: https://doi.org/10.1002/joa3.12992
- DOI: https://doi.org/10.1111/jce.16408
- DOI: https://doi.org/10.1111/jce.16415
- DOI: https://doi.org/10.1007/s10840-024-01845-4
- DOI: https://doi.org/10.1002/joa3.13070
- DOI: https://doi.org/10.1002/joa3.13070
- [2024] Electrocardiogram predictors of leadless pacemaker implantation in the right ventricular free wallDOI: https://doi.org/10.1093/europace/euae102.396
- [2024] Electrocardiogram predictors of leadless pacemaker implantation in the right ventricular free wallDOI: https://doi.org/10.1093/europace/euae102.396
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.416
- DOI: https://doi.org/10.1016/j.hrthm.2024.03.1374
- DOI: https://doi.org/10.1002/joa3.13040
- DOI: https://doi.org/10.1111/jce.15875
- DOI: https://doi.org/10.1111/pace.14859
- DOI: https://doi.org/10.1111/jce.15964
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1019
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1215
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1011
- [2023] PO-04-133 IMPACT OF A CLOSE INDIFFERENT ELECTRODE ON ATRIAL UNIPOLAR AND BIPOLAR ELECTROGRAMSDOI: https://doi.org/10.1016/j.hrthm.2023.03.1178
- DOI: https://doi.org/10.1002/ccr3.7392
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.778
- DOI: https://doi.org/10.1111/pace.14868
- DOI: https://doi.org/10.1093/europace/euad365
- DOI: https://doi.org/10.1093/europace/euad365
- DOI: https://doi.org/10.1111/pace.14868
- DOI: https://doi.org/10.1007/s10840-023-01678-7
- DOI: https://doi.org/10.1253/circj.cj-23-0574
- DOI: https://doi.org/10.1253/circj.cj-23-0574
- DOI: https://doi.org/10.1111/pace.14859
- DOI: https://doi.org/10.1002/clc.24164
- DOI: https://doi.org/10.1161/circep.123.012241
- DOI: https://doi.org/10.1016/j.jacep.2023.06.018
- DOI: https://doi.org/10.1111/jce.15997
- DOI: https://doi.org/10.1002/clc.24164
- DOI: https://doi.org/10.1161/circep.123.012241
- DOI: https://doi.org/10.1016/j.jacep.2023.06.018
- DOI: https://doi.org/10.1111/jce.15997
- DOI: https://doi.org/10.1093/europace/euad195
- DOI: https://doi.org/10.1093/europace/euad195
- DOI: https://doi.org/10.1111/jce.15964
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1019
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1215
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.1011
- [2023] PO-04-133 IMPACT OF A CLOSE INDIFFERENT ELECTRODE ON ATRIAL UNIPOLAR AND BIPOLAR ELECTROGRAMSDOI: https://doi.org/10.1016/j.hrthm.2023.03.1178
- DOI: https://doi.org/10.1002/ccr3.7392
- DOI: https://doi.org/10.1016/j.hrthm.2023.03.778
- DOI: https://doi.org/10.5105/jse.43.36
- DOI: https://doi.org/10.5105/jse.43.36
- DOI: https://doi.org/10.1111/jce.15883
- DOI: https://doi.org/10.1111/jce.15875
- DOI: https://doi.org/10.1111/pace.14665
- DOI: https://doi.org/10.1111/jce.15883
- DOI: https://doi.org/10.1007/s10840-023-01678-7
- DOI: https://doi.org/10.1111/pace.14665
- DOI: https://doi.org/10.1016/j.hrthm.2022.01.016
- DOI: https://doi.org/10.1007/s10840-022-01282-1
- DOI: https://doi.org/10.1111/pace.14613
- DOI: https://doi.org/10.1016/j.hrthm.2022.11.003
- DOI: https://doi.org/10.1016/j.jccase.2022.10.014
- DOI: https://doi.org/10.1016/j.jccase.2022.10.014
- DOI: https://doi.org/10.1016/j.hrthm.2022.11.003
- DOI: https://doi.org/10.1111/pace.14613
- DOI: https://doi.org/10.1093/europace/euac195
- DOI: https://doi.org/10.1016/j.jacep.2022.07.011
- DOI: https://doi.org/10.1016/j.hrthm.2022.07.026
- DOI: https://doi.org/10.1055/s-0042-1751230
- DOI: https://doi.org/10.1007/s10840-022-01282-1
- DOI: https://doi.org/10.1007/s10840-022-01251-8
- DOI: https://doi.org/10.1016/j.hrcr.2022.05.005
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.237
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.495
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.384
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.954
- DOI: https://doi.org/10.1007/s10840-022-01219-8
- DOI: https://doi.org/10.1007/s10840-022-01214-z
- DOI: https://doi.org/10.1055/s-0042-1751230
- DOI: https://doi.org/10.1093/europace/euac195
- DOI: https://doi.org/10.1016/j.jacep.2022.07.011
- DOI: https://doi.org/10.1016/j.hrthm.2022.07.026
- DOI: https://doi.org/10.1111/pace.14542
- DOI: https://doi.org/10.1016/j.ipej.2022.05.003
- DOI: https://doi.org/10.1007/s10840-022-01251-8
- DOI: https://doi.org/10.1016/j.hrcr.2022.05.005
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.237
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.495
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.384
- DOI: https://doi.org/10.1016/j.hrthm.2022.03.954
- DOI: https://doi.org/10.1007/s10840-022-01219-8
- DOI: https://doi.org/10.1007/s10840-022-01214-z
- DOI: https://doi.org/10.1016/j.hrthm.2022.01.016
- DOI: https://doi.org/10.1111/pace.14542
- DOI: https://doi.org/10.1016/j.ipej.2022.05.003
- DOI: https://doi.org/10.1111/jce.15262
- DOI: https://doi.org/10.1111/pace.14425
- DOI: https://doi.org/10.1016/j.hrthm.2021.09.011
- DOI: https://doi.org/10.1016/j.hrthm.2021.06.1202
- DOI: https://doi.org/10.1016/j.jaccas.2021.04.023
- DOI: https://doi.org/10.1111/pace.14425
- DOI: https://doi.org/10.1111/jce.15262
- DOI: https://doi.org/10.1016/j.hrthm.2021.09.011
- DOI: https://doi.org/10.1111/jce.15186
- DOI: https://doi.org/10.1016/j.hrthm.2021.06.1202
- DOI: https://doi.org/10.1016/j.jaccas.2021.04.023
- DOI: https://doi.org/10.1111/jce.15186
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