Mamoru Tobisu 研究室

主宰者：Mamoru Tobisu

大阪大学

AI 要約（直近 5 年の研究成果）

本研究室は、有機化学における新しい反応の開発と、そのメカニズム解明に取り組んでいます。特に、従来の遷移金属触媒反応では実現困難だった変換を、主族元素（ガリウムやインジウムなどの13族元素）や非典型的な反応過程を利用して達成することを目指しています。光をエネルギー源とした反応や、分子内で原子を除去してから断片を結合させる戦略など、従来の有機合成化学の枠を超えた方法論を探索しています。また、独特の性質を持つ有機ケイ素化合物（アシルシランなど）の炭素－ケイ素結合を活性化する金属触媒反応も重要なテーマです。これらの反応を通じて、医薬品や機能性材料の合成に必要な複雑な骨格を効率よく構築する手法を開発しています。加えて、環境課題への対応として、高分子化合物を触媒的に分解して再利用可能なモノマーに戻すプラスチック・リサイクル技術の研究も進めており、持続可能な化学への貢献を目指しています。これらの研究を支える基礎として、新しい配位子設計や金属錯体の合成・評価も行われています。さらに、金属塩や錯体の電子的性質を詳細に調べることで、より効果的で選択的な触媒システムの開発に役立てています。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

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研究成果（69 件）

[2026] A novel turn-on fluorescent sensor based on a thiazoline–amidoquinoline derivative for Zn 2+ detection in dietary supplements and macrophage cells
DOI: https://doi.org/10.1039/d6ma00558f
[2026] Structure–Stability Relationships in Sulfonamide Electrolyte Solvents for Lithium–Oxygen Batteries: Limited Impact of α-Hydrogen and Dominant Role of Alkyl Chain Decomposition
DOI: https://doi.org/10.5796/electrochemistry.26-74042
[2026] Photoinduced Disproportionation Enables Oxidative Addition of Aryl Iodides at a Gallium(I) Center
DOI: https://doi.org/10.1021/jacs.6c08303
[2026] Synthesis, Structure, and Reactivity of a Neutral Indium(I) Complex Bearing a Phenalenyl-Based N,N-Bidentate Ligand
DOI: https://doi.org/10.1021/acs.inorgchem.6c00601
[2026] Visible-light-induced GaC bond homolysis in dialkylgallium(III) complexes and photochemical generation of a gallylene
DOI: https://doi.org/10.1016/j.tetlet.2026.156110
[2025] Cobalt‐Catalyzed Decarbonylation of Aromatic Acylsilanes via the Cleavage of Carbon–Silicon Bonds
DOI: https://doi.org/10.1002/asia.202500875
[2025] β-Arylation of Indanone Derivatives via α-Carbamoylation/Elimination of Isocyanate Sequence
DOI: https://doi.org/10.1021/acs.joc.5c01130
[2025] A dual sensing probe for Cd2+ and Zn2+ detection in water based on tautomerization of acetamidoquinoline containing dipicolylamine and its application in water samples and cell imaging
DOI: https://doi.org/10.1016/j.sintl.2025.100336
[2025] Synthesis of Polyamides Bearing Directing Groups and Their Catalytic Depolymerization
DOI: https://doi.org/10.1021/acs.orglett.4c04829
[2025] Generation of Stereocenters via Single-Carbon-Atom Doping Using N -Isocyanides
DOI: https://doi.org/10.1021/jacs.5c00882

続きを表示（残り 59 件）

[2025] Directing Group-Integrated Poly(phenylene sulfide): Achieving Chemical Stability and Controlled Degradability
DOI: https://doi.org/10.1021/acs.macromol.5c00051
[2025] Unimolecular Fragment Coupling and Single Carbon Atom Doping as Tools for Structural Reprogramming
DOI: https://doi.org/10.1021/acs.accounts.5c00050
[2025] Recent Advances in Metal-Catalyzed Transformations of Acylsilanes via the Activation of C–Si Bonds
DOI: https://doi.org/10.1021/acscatal.5c01808
[2025] Aryne Polymerization Enabled by Pyrazole-Induced Nucleophilic Aromatic Substitution
DOI: https://doi.org/10.1021/jacs.5c03980
[2025] Synthesis of Phenylenediamines via (4 + 1 + 1) Photocycloaddition of 1,3-Dienes and Isocyanides Enabled by a Gallium(I)/(III) Redox: The Key Role of a Phenalenyl-Based Ligand
DOI: https://doi.org/10.1021/jacs.5c15802
[2025] Nickel-catalyzed decarbonylative addition of acylsilanes across alkynes via the cleavage of a carbon–silicon bond
DOI: https://doi.org/10.1039/d5sc07524f
[2024] Catalytic synthesis of β-lactam derivatives by carbonylative cycloaddition of acylsilanes with imines via a palladium Fischer-carbene intermediate
DOI: https://doi.org/10.1038/s41929-023-01081-5
[2024] Unimolecular Fragment Coupling: A New Bond-Forming Methodology via the Deletion of Atom(s)
DOI: https://doi.org/10.1021/jacsau.3c00827
[2024] KOtBu-Catalyzed Synthesis of Isoindole Derivatives from N-Benzyl Amides Bearing an Ortho Alkynyl Group via 1,2-Acyl Shift
DOI: https://doi.org/10.1021/acs.orglett.4c02055
[2024] Cu(II) detection by a fluorometric probe based on thiazoline-amidoquinoline derivative and its application to water and food samples
DOI: https://doi.org/10.1016/j.saa.2024.124706
[2024] Fluorinated Amide-Based Electrolytes Induce a Sustained Low-Charging Voltage Plateau under Conditions Verifying the Feasibility of Achieving 500 Wh kg–1 Class Li–O2 Batteries
DOI: https://doi.org/10.1021/acsami.4c08067
[2024] Expanding the Design Flexibility of Electrolyte Solvents for Li–O2 Secondary Batteries by Incorporating Fluorine Groups
DOI: https://doi.org/10.1021/acsaem.4c02421
[2024] Generation of Nickel Siloxycarbene Complexes from Acylsilanes for the Catalytic Synthesis of Silyl Enol Ethers
DOI: https://doi.org/10.1021/acscatal.4c06272
[2024] A nickel metalloradical bearing a phenalenyl-based tridentate ligand
DOI: https://doi.org/10.1093/chemle/upae236
[2024] Synthesis and characterization of alkali metal salts bearing a phenalenyl-based tridentate ligand
DOI: https://doi.org/10.1093/chemle/upae246
[2024] Cationic nickel(II) complexes bearing a phenalenyl-based tridentate ligand
DOI: https://doi.org/10.1093/chemle/upae251
[2024] Transition-Metal Catalyzed Unimolecular Fragment Couplings
DOI: https://doi.org/10.5059/yukigoseikyokaishi.82.450
[2024] Cover Feature: Single‐Carbon Atom Doping Reactions Using Atomic Carbon and Its Equivalents (ChemistryEurope 3‐4/2024)
DOI: https://doi.org/10.1002/ceur.202400044
[2024] Single‐Carbon Atom Doping Reactions Using Atomic Carbon and Its Equivalents
DOI: https://doi.org/10.1002/ceur.202400005
[2024] Palladium-Catalyzed Addition of Trifluoroacetylsilanes to Alkenes and Allenes via the Cleavage of C–Si Bonds
DOI: https://doi.org/10.1021/acs.orglett.4c00595
[2024] Controlled degradation of chemically stable poly(aryl ethers) via directing group-assisted catalysis
DOI: https://doi.org/10.1039/d4sc04147j
[2023] Non-Classical Molecular Activation by Phosphines and N-Heterocyclic Carbenes and Its Application to Catalytic Reactions
DOI: https://doi.org/10.1246/bcsj.20230150
[2023] Synthesis and Host–Guest Chemistry of Chiral Spirobifluorene-Based Macrocycles Soluble in Basic Aqueous Solution
DOI: https://doi.org/10.1021/acs.orglett.3c02074
[2023] Palladium-catalyzed addition of acylsilanes across alkynes via the activation of a C–Si bond
DOI: https://doi.org/10.1039/d3sc00181d
[2023] A novel “turn-on” fluorescent probe based on thiocarbamoyl-DHP for Hg2+ detection in water samples and living cells
DOI: https://doi.org/10.1016/j.saa.2023.123783
[2023] Synthesis of γ-Lactams from Acrylamides by Single-Carbon Atom Doping Annulation
DOI: https://doi.org/10.1021/jacs.3c07052
[2023] Nickel/Photoredox Dual-Catalyzed Conversion of Allyl Esters to Ketones via the Formal Deletion of Oxygen
DOI: https://doi.org/10.1021/acs.orglett.3c02606
[2023] Nickel-catalyzed direct methylation of arylphosphines via carbon–phosphorus bond cleavage using AlMe 3
DOI: https://doi.org/10.1039/d3cc02455e
[2023] Open-Shell Germylene Stabilized by a Phenalenyl-Based Ligand
DOI: https://doi.org/10.1021/acs.inorgchem.3c00583
[2023] Synthesis, Structure, and Reactivity of a Gallylene Derivative Bearing a Phenalenyl-Based Ligand
DOI: https://doi.org/10.1021/acs.inorgchem.3c00697
[2023] Cationic Rhodium(I) Tetrafluoroborate Catalyzed Intramolecular Carbofluorination of Alkenes via Acyl Fluoride C−F Bond Activation**
DOI: https://doi.org/10.1002/anie.202303657
[2023] Cationic Rhodium(I) Tetrafluoroborate Catalyzed Intramolecular Carbofluorination of Alkenes via Acyl Fluoride C−F Bond Activation**
DOI: https://doi.org/10.1002/ange.202303657
[2023] Oxovanadium(V)‐Catalyzed Deoxygenative Coupling Reaction of Alcohols with Trimethylsilyl Enol Ethers in the Presence of MS3A
DOI: https://doi.org/10.1002/ejoc.202201410
[2023] Single–carbon atom transfer to α,β-unsaturated amides from N-heterocyclic carbenes
DOI: https://doi.org/10.1126/science.ade5110
[2023] Palladium-Catalyzed Unimolecular Fragment Coupling of N-Allylamides Bearing a Tethered Nucleophile with the Translocation of an Amide Group
DOI: https://doi.org/10.1055/a-2022-1905
[2023] 1,2-Diacylation of Alkynes Using Acyl Fluorides and Acylsilanes by P(III)/P(V) Catalysis
DOI: https://doi.org/10.1021/acs.orglett.2c03910
[2022] Palladium‐Catalyzed Silylacylation of Allenes Using Acylsilanes
DOI: https://doi.org/10.1002/anie.202202387
[2022] Palladium-Catalyzed Unimolecular Fragment Coupling of N-Allylamides via Elimination of Isocyanate
DOI: https://doi.org/10.1021/jacs.2c04527
[2022] Phosphine-Catalyzed Z-Selective Carbofluorination of Alkynoates Bearing an N-Heteroarene Unit
DOI: https://doi.org/10.1055/a-1948-3234
[2022] Pd-catalyzed siloxycyclopropanation of alkenes
DOI: https://doi.org/10.1016/j.trechm.2022.08.011
[2022] Rhodium‐catalyzed Decarbonylation of Acylsilanes
DOI: https://doi.org/10.1002/ajoc.202200610
[2022] Zn(II)-catalyzed Formal Cross-dimerization of Carbenes Using Acylsilanes and Diazo Esters
DOI: https://doi.org/10.1246/cl.220476
[2022] A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au3+ Residue in Gold Nanoparticle Solution
DOI: https://doi.org/10.3390/s23010436
[2022] Overlooked Factors Required for Electrolyte Solvents in Li–O2 Batteries: Capabilities of Quenching 1O2 and Forming Highly‐Decomposable Li2O2
DOI: https://doi.org/10.1002/anie.202112769
[2022] Overlooked Factors Required for Electrolyte Solvents in Li–O2 Batteries: Capabilities of Quenching 1O2 and Forming Highly‐Decomposable Li2O2
DOI: https://doi.org/10.1002/ange.202112769
[2022] Palladium-Catalyzed Siloxycyclopropanation of Alkenes Using Acylsilanes
DOI: https://doi.org/10.1021/jacs.1c11497
[2022] Nickel-Catalyzed Addition of C–C Bonds of Amides to Strained Alkenes: The 1,2-Carboaminocarbonylation Reaction
DOI: https://doi.org/10.1021/jacs.1c09265
[2022] Nickel-catalyzed skeletal transformation of tropone derivatives via C–C bond activation: catalyst-controlled access to diverse ring systems
DOI: https://doi.org/10.1039/d2sc01394k
[2022] Nickel-catalyzed 1,4-aryl rearrangement of aryl N -benzylimidates via C–O and C–H bond cleavage
DOI: https://doi.org/10.1039/d2cc02355e
[2022] Palladium‐Catalyzed Silylacylation of Allenes Using Acylsilanes
DOI: https://doi.org/10.1002/ange.202202387
[2022] Non-Stabilized Vinyl Anion Equivalents from Styrenes by N-Heterocyclic Carbene Catalysis and Its Use in Catalytic Nucleophilic Aromatic Substitution
DOI: https://doi.org/10.1021/jacs.2c02579
[2021] Late-Stage Derivatization of Buflavine by Nickel-Catalyzed Direct Substitution of a Methoxy Group via C–O Bond Activation
DOI: https://doi.org/10.1055/a-1467-2494
[2021] Synthesis of 4,5-Benzotropone π Complexes of Iron, Rhodium, and Iridium and Their Potential Use in Catalytic Borrowing-Hydrogen Reactions
DOI: https://doi.org/10.1021/acs.inorgchem.0c03587
[2021] Ruthenium-Catalyzed Isomerization of ortho-Silylanilines to Their para Isomers
DOI: https://doi.org/10.1021/acs.orglett.1c02280
[2021] Synthesis and Characterization of 1-Hydroxy-4,5-arene-Fused Tropylium Derivatives
DOI: https://doi.org/10.1021/acs.joc.1c01818
[2021] Oxovanadium( <scp>v</scp> )-catalyzed amination of carbon dioxide under ambient pressure for the synthesis of ureas
DOI: https://doi.org/10.1039/d1ra04125h
[2021] Three-Component Coupling of Acyl Fluorides, Silyl Enol Ethers, and Alkynes by P(III)/P(V) Catalysis
DOI: https://doi.org/10.1021/jacs.1c10042
[2021] Ratiometric and colorimetric detection of Cu2+ via the oxidation of benzodihydroquinoline derivatives and related synthetic methodology
DOI: https://doi.org/10.1016/j.sbsr.2021.100470
[2021] N-Heterocyclic Carbene-Catalyzed Truce–Smiles Rearrangement of N-Arylacrylamides via the Cleavage of Unactivated C(aryl)–N Bonds
DOI: https://doi.org/10.1021/acs.orglett.0c04281

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AI 要約（直近 5 年の研究成果）

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研究成果（69 件）

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