Kohei Hasegawa 研究室

主宰者：Kohei Hasegawa

信州大学

AI 要約（直近 5 年の研究成果）

長谷川研究室は、環境要因が人間の健康に与える影響を明らかにする研究を行っています。特に、妊娠中や乳幼児期の環境への曝露と、その後の子どもの健康状態との関連性に焦点を当てています。具体的には、化学物質や大気汚染などへの母体曝露が、胎児や出生後の子どもの成長発達に及ぼす影響を調査しており、大規模な日本の出生コホート研究やいくつかの医療保険データベースを活用した疫学研究を展開しています。研究方法としては、出生時や乳幼児期に収集された血液や尿などの生体試料の分析、医療機関の受診記録や健康診断データの統計解析、さらには血液中の様々な分子の網羅的測定といった手法を組み合わせています。こうした多角的なアプローチにより、環境曝露と小児期の機能性便秘、代謝異常、歯の健康状態など様々な健康アウトカムとの関連を明らかにしています。また同研究室は、心臓病患者の予後予測に向けた分子レベルの解析にも取り組んでおり、複数の大規模集団を対象とした疫学調査と分子生物学的手法の組み合わせが特徴です。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

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研究成果（35 件）

[2026] Placental histopathology and early childhood neurodevelopment in the Environmental influences on Child Health Outcomes cohort
DOI: https://doi.org/10.1016/j.ajog.2026.02.024
[2026] Associations between maternal exposure to per- and polyfluoroalkyl substances and functional constipation in children at 3 and 4 years: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1265/ehpm.25-00399
[2025] Air Pollution Exposure and Birth Weight in the ECHO Cohort
DOI: https://doi.org/10.1001/jamanetworkopen.2025.51459
[2025] Prenatal mercury exposure and body mass index at 2 and 4 years: The Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.ijheh.2025.114566
[2025] Broadband characteristics of Pacific herring (Clupea pallasii) and Pacific chub mackerel (Scomber japonicus) target strength identified using the tether method
DOI: https://doi.org/10.1016/j.fishres.2025.107306
[2024] PREDICTION OF NEW-ONSET ATRIAL FIBRILLATION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY USING MACHINE LEARNING
DOI: https://doi.org/10.1016/s0735-1097(24)02496-3
[2024] Hypertensive disorders of pregnancy increase the incidence of febrile seizures in offspring
DOI: https://doi.org/10.1038/s41390-024-03057-y
[2024] Associations between maternal per- and polyfluoroalkyl substances exposure and lipid levels in maternal and cord blood: The Japan environment and Children's study
DOI: https://doi.org/10.1016/j.envres.2024.120217
[2024] Association between relatively low blood lead levels and urinary δ-aminolevulinic acid concentrations among male workers at a Japanese battery factory
DOI: https://doi.org/10.1093/joccuh/uiae056
[2024] Association of density and sound-speed contrast with maturity stage of Antarctic krill in the eastern Indian sector of the Southern Ocean
DOI: https://doi.org/10.1007/s12562-024-01819-5

続きを表示（残り 25 件）

[2024] Maternal Exposure to Per- and Polyfluoroalkyl Substances and Offspring Chromosomal Abnormalities: The Japan Environment and Children’s Study
DOI: https://doi.org/10.1289/ehp13617
[2024] Prenatal mercury exposure and the secondary sex ratio: The Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.reprotox.2024.108685
[2024] P-198 3,3’-DICHLORO-4,4’-DIAMINODIPHENYLMETHANE (MBOCA) EXPOSURE AND BIOLOGICAL MONITORING IN JAPANESE WORKERS
DOI: https://doi.org/10.1093/occmed/kqae023.0740
[2024] Study on Influence of Leakage Flux Dependence on Winding Position of Common-mode Choke Coil Using Toroidal Core
DOI: https://doi.org/10.23919/emcjapan/apemcokinaw58965.2024.10585033
[2023] Impact of dog and/or cat ownership on functional constipation at 3 years of age: the Japan Environment and Children’s study
DOI: https://doi.org/10.1186/s12887-023-04412-4
[2023] Abstract 12822: Prediction of New-Onset Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy Using RNA-Sequencing of Plasma Small Non-Coding RNAs
DOI: https://doi.org/10.1161/circ.148.suppl_1.12822
[2023] Impact of breastfeeding during infancy on functional constipation at 3 years of age: the Japan Environment and Children’s Study
DOI: https://doi.org/10.1186/s13006-023-00592-y
[2023] Association between the number of teeth and incident pre-diabetes among middle-aged adults with periodontal disease: a retrospective cohort analysis of Japanese claims data
DOI: https://doi.org/10.1136/bmjopen-2023-075527
[2023] Measurements and Theoretical Model Simulation of Target Strength of Pacific Chub Mackerel for Use in a Quantitative Sonar
DOI: https://doi.org/10.3135/jmasj.50.107
[2023] Associations between long-term care-service use and service- or care-need level progression: a nationwide cohort study using the Japanese Long-Term Care Insurance Claims database
DOI: https://doi.org/10.1186/s12913-023-09615-0
[2023] Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities
DOI: https://doi.org/10.1016/j.ecoenv.2023.114961
[2023] Broadband target strength of arabesque greenling, Pacific sand lance, and pointhead flounder
DOI: https://doi.org/10.1093/icesjms/fsad195
[2023] Associations between prenatal exposure to per- and polyfluoroalkyl substances and wheezing and asthma symptoms in 4-year-old children: The Japan Environment and Children's Study
DOI: https://doi.org/10.1016/j.envres.2023.117499
[2022] Magnetic Saturation Suppression of Common-Mode Choke Coil by Selecting Suitable Inverter Carrier Frequency
DOI: https://doi.org/10.1541/ieejjia.21009004
[2022] A case report of COVID-19 preventive measures at an academic meeting of the Japan Society for Occupational Health
DOI: https://doi.org/10.1539/sangyoeisei.2022-019-d
[2022] Short-term associations of ambient air pollution with hospital admissions for ischemic stroke in 97 Japanese cities
DOI: https://doi.org/10.1007/s11356-022-21206-w
[2022] Magnetic Saturation Suppression of Common-Mode Choke Coil by Selecting Suitable Inverter Carrier Frequency
DOI: https://doi.org/10.1541/ieejias.142.362
[2022] A Prototype Target Strength Measuring System for Small Organisms Using an Acrylic Water Tank
DOI: https://doi.org/10.3135/jmasj.49.37
[2022] Three-year trajectories of body mass index before a diagnosis of sleep apnea syndrome: A nested case-control study in middle-aged male Japanese workers
DOI: https://doi.org/10.1016/j.shaw.2021.12.1153
[2022] Effects of 1-bromopropane on the vibration perception thresholds of male workers
DOI: https://doi.org/10.1016/j.shaw.2021.12.1517
[2021] Abstract 13312: Comprehensive Sequencing of Small Non-Coding RNA Reveals Plasma Circulating Biomarkers of Hypertrophic Cardiomyopathy and Dysregulated Signaling Pathways
DOI: https://doi.org/10.1161/circ.144.suppl_1.13312
[2021] Proteomics profiling reveals distinct molecular subtypes of hypertrophic cardiomyopathy with differential risks of major adverse cardiovascular events
DOI: https://doi.org/10.1093/eurheartj/ehab724.1765
[2021] In situ broadband acoustic measurements of age-0 walleye pollock and pointhead flounder in Funka Bay, Hokkaido, Japan
DOI: https://doi.org/10.51400/2709-6998.1076
[2021] Short-Term Associations of Ambient Fine Particulate Matter (PM2.5) with All-Cause Hospital Admissions and Total Charges in 12 Japanese Cities
DOI: https://doi.org/10.3390/ijerph18084116
[2021] Association between Air Pollutants and Cancer Incidence Rates in Japan: An Ecological Study
DOI: https://doi.org/10.3390/ecerph-3-09054

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AI 要約（直近 5 年の研究成果）

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関連研究室(8 件)

研究成果（35 件）

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