Motomu Kanai 研究室

主宰者：Motomu Kanai

東京大学

兼任：熊本大学

AI 要約（直近 5 年の研究成果）

本研究室は、光やラジカル反応を利用した化学触媒を開発し、生命現象の解明と治療法の開発に応用する研究を行っています。特に、生きた細胞や生体内で機能する触媒システムの設計に注力しており、遺伝子操作に頼らない化学的アプローチで生体分子を選択的に変化させる技術を追求しています。主な研究の課題は、温和な条件で高い活性と選択性を兼ね備えた触媒を実現することです。例えば、光を当てるだけでタンパク質上の特定のアミノ酸を認識して化学修飾を加える触媒や、酵素のような精密性で有機分子を合成する触媒システムを開発しています。これらの触媒は、分子のどこをどのように変えるかを正確に制御でき、複雑な生体環境でも目的の反応を進めることができるよう設計されています。さらに、本研究室は開発した触媒を実際の医療課題に応用する試みも展開しています。アルツハイマー病やATTR型アミロイドーシスなどの神経変性疾患において、異常に集積したタンパク質を光触媒で選択的に変性させることで、症状改善の可能性を示唆する成果も報告しています。化学的な道具立てで生命現象に直接働きかけ、基礎科学と応用医療の橋渡しを目指す研究室です。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

外部リンク

研究成果（149 件）

[2026] Photocatalytic RNA Depyrimidination
DOI: https://doi.org/10.26434/chemrxiv.15003007/v1
[2026] Synthesis ofDNA-Encoded Libraries by Tryptophan-SelectiveBioconjugation
DOI: https://doi.org/10.1021/acs.orglett.6c02201.s001
[2026] Synthesis of DNA-Encoded Libraries by Tryptophan-Selective Bioconjugation
DOI: https://doi.org/10.1021/acs.orglett.6c02201
[2026] Duocarmycin‐Bearing Antibody‐Mimetic Drug Conjugate Combined With an <scp>ATR</scp> Inhibitor Results in Complete Tumor Regression in a <scp>KPL</scp> ‐4 Xenograft Model
DOI: https://doi.org/10.1002/cam4.72071
[2026] Catalytic strategies for post-translational modifications regulating protein higher-order structure and properties
DOI: https://doi.org/10.1039/d6cs00107f
[2025] Electron Donor–Acceptor (EDA) Complex Formation via Spatial Control of Donor–Acceptor Interactions
DOI: https://doi.org/10.1021/acs.joc.5c02351
[2025] Ion‐Pair Hydrogen Atom Transfer Catalysis Enables Cr‐Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes
DOI: https://doi.org/10.1002/anie.202503249
[2025] Ion‐Pair Hydrogen Atom Transfer Catalysis Enables Cr‐Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes
DOI: https://doi.org/10.1002/ange.202503249
[2025] Catalytic Phosphorylation of Tyrosine via a Radical Arbuzov Reaction
DOI: https://doi.org/10.1021/jacs.4c17637
[2025] A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
DOI: https://doi.org/10.1002/anie.202500162

続きを表示（残り 139 件）

[2025] A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
DOI: https://doi.org/10.1002/ange.202500162
[2025] Ion‐Pair Hydrogen Atom Transfer Catalysis Enables Cr‐Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes
DOI: https://doi.org/10.1002/anie.202503249
[2025] Ion‐Pair Hydrogen Atom Transfer Catalysis Enables Cr‐Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes
DOI: https://doi.org/10.1002/ange.202503249
[2025] Chemical catalyst manipulating cancer epigenome and transcription
DOI: https://doi.org/10.1038/s41467-025-56204-2
[2025] Spectral control of photoenzyme through allosteric chromophore tuning
DOI: https://doi.org/10.1016/j.chempr.2025.102430
[2025] Catalytic Phosphorylation of Tyrosine via a Radical Arbuzov Reaction
DOI: https://doi.org/10.1021/jacs.4c17637
[2025] Chemical catalyst manipulating cancer epigenome and transcription
DOI: https://doi.org/10.1038/s41467-025-56204-2
[2025] Spectral control of photoenzyme through allosteric chromophore tuning
DOI: https://doi.org/10.1016/j.chempr.2025.102430
[2025] Catalytic acceptorless complete dehydrogenation of cycloalkanes
DOI: https://doi.org/10.1038/s41467-024-55460-y
[2025] A reflection on ketoABNO: the crossing point between organic synthesis and protein modification
DOI: https://doi.org/10.1039/d5sc90203g
[2025] Catalytic acceptorless complete dehydrogenation of cycloalkanes
DOI: https://doi.org/10.1038/s41467-024-55460-y
[2025] A reflection on ketoABNO: the crossing point between organic synthesis and protein modification
DOI: https://doi.org/10.1039/d5sc90203g
[2025] Chemical Catalysis To Address Biological Questions and Therapeutic Challenges
DOI: https://doi.org/10.1021/acscatal.5c07625
[2025] Azaanthraquinone PCET Catalysis Enables Chemoselective Decarboxylative Functionalization of Diverse Carboxylic Acids
DOI: https://doi.org/10.1021/jacs.5c10807
[2025] Photocatalytic phosphorylation of alcohols via oxidative activation of 1,4-dihydropyridine-N-phosphoramide
DOI: https://doi.org/10.1016/j.tet.2025.135008
[2025] Visible light–driven stereodivergent allylation of cyclic hemiacetals with butene for polypropionate synthesis
DOI: https://doi.org/10.1126/science.adz0686
[2025] Chemical Catalysis To Address Biological Questions and Therapeutic Challenges
DOI: https://doi.org/10.1021/acscatal.5c07625
[2025] Electron Donor–Acceptor (EDA) Complex Formation via Spatial Control of Donor–Acceptor Interactions
DOI: https://doi.org/10.1021/acs.joc.5c02351
[2025] Azaanthraquinone PCET Catalysis Enables Chemoselective Decarboxylative Functionalization of Diverse Carboxylic Acids
DOI: https://doi.org/10.1021/jacs.5c10807
[2025] Photocatalytic phosphorylation of alcohols via oxidative activation of 1,4-dihydropyridine-N-phosphoramide
DOI: https://doi.org/10.1016/j.tet.2025.135008
[2025] Visible light–driven stereodivergent allylation of cyclic hemiacetals with butene for polypropionate synthesis
DOI: https://doi.org/10.1126/science.adz0686
[2025] Condensate-enhanced catalytic photo-oxygenation for early intervention in tau amyloidosis
DOI: https://doi.org/10.26434/chemrxiv-2025-r5qm4
[2025] Catalytic Photooxygenation Demonstrates Therapeutic Efficacy in Transthyretin Amyloidosis
DOI: https://doi.org/10.1021/jacs.5c06205
[2025] Induced Bioconjugation via On-Demand Isocyanate Formation
DOI: https://doi.org/10.1021/jacs.5c11603
[2025] (Invited) Double Hydrogen Atom Transfer Strategy for Catalytic Acceptorless Dehydrogenation of Cycloalkanes
DOI: https://doi.org/10.1149/ma2025-01161208mtgabs
[2025] Designer Catalyst-Enabled Regiodivergent Histone Acetylation
DOI: https://doi.org/10.1021/jacs.5c01699
[2025] Condensate-enhanced catalytic photo-oxygenation for early intervention in tau amyloidosis
DOI: https://doi.org/10.26434/chemrxiv-2025-r5qm4
[2025] Catalytic Photooxygenation Demonstrates Therapeutic Efficacy in Transthyretin Amyloidosis
DOI: https://doi.org/10.1021/jacs.5c06205
[2025] Induced Bioconjugation via On-Demand Isocyanate Formation
DOI: https://doi.org/10.1021/jacs.5c11603
[2025] (Invited) Double Hydrogen Atom Transfer Strategy for Catalytic Acceptorless Dehydrogenation of Cycloalkanes
DOI: https://doi.org/10.1149/ma2025-01161208mtgabs
[2025] Designer Catalyst-Enabled Regiodivergent Histone Acetylation
DOI: https://doi.org/10.1021/jacs.5c01699
[2025] A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
DOI: https://doi.org/10.1002/anie.202500162
[2025] A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
DOI: https://doi.org/10.1002/ange.202500162
[2024] Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids
DOI: https://doi.org/10.1002/ange.202405605
[2024] Leuco Ethyl Violet as Self‐Activating Prodrug Photocatalyst for In Vivo Amyloid‐Selective Oxygenation
DOI: https://doi.org/10.1002/advs.202401346
[2024] Redesign of a thioflavin-T-binding protein with a flat β-sheet to evaluate a thioflavin-T-derived photocatalyst with enhanced affinity
DOI: https://doi.org/10.1016/j.ijbiomac.2024.131992
[2024] Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids
DOI: https://doi.org/10.1002/anie.202405605
[2024] Redesign of a thioflavin-T-binding protein with a flat β-sheet to evaluate a thioflavin-T-derived photocatalyst with enhanced affinity
DOI: https://doi.org/10.1016/j.ijbiomac.2024.131992
[2024] Leuco Ethyl Violet as Self‐Activating Prodrug Photocatalyst for In Vivo Amyloid‐Selective Oxygenation
DOI: https://doi.org/10.1002/advs.202401346
[2024] Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids
DOI: https://doi.org/10.1002/ange.202405605
[2024] In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin
DOI: https://doi.org/10.1016/j.bmcl.2024.129803
[2024] Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids
DOI: https://doi.org/10.1002/anie.202405605
[2024] Copper(I)-Catalyzed Asymmetric Nucleophilic Addition to Aldehydes with Skipped Enynes
DOI: https://doi.org/10.1021/acs.orglett.4c03449
[2024] Umpolung Phosphorylation of Tyrosine via 1,2-Phospha-Brook Rearrangement
DOI: https://doi.org/10.1021/acs.orglett.4c03223
[2024] Copper(I)-Catalyzed Asymmetric Nucleophilic Addition to Aldehydes with Skipped Enynes
DOI: https://doi.org/10.1021/acs.orglett.4c03449
[2024] Umpolung Phosphorylation of Tyrosine via 1,2-Phospha-Brook Rearrangement
DOI: https://doi.org/10.1021/acs.orglett.4c03223
[2024] (Invited) Development of Leuco Ethyl Violet as Self-Activating Prodrug Photooxygenation Catalyst of Amyloid-β
DOI: https://doi.org/10.1149/ma2024-01131037mtgabs
[2024] In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin
DOI: https://doi.org/10.1016/j.bmcl.2024.129803
[2024] (Invited) Development of Leuco Ethyl Violet as Self-Activating Prodrug Photooxygenation Catalyst of Amyloid-β
DOI: https://doi.org/10.1149/ma2024-01131037mtgabs
[2023] Modulation of the functional interfaces between retroviral intasomes and the human nucleosome
DOI: https://doi.org/10.1128/mbio.01083-23
[2023] Photo‐oxygenation of histidine residue inhibits α‐synuclein aggregation
DOI: https://doi.org/10.1096/fj.202301533r
[2023] Practical N-to-C peptide synthesis with minimal protecting groups
DOI: https://doi.org/10.1038/s42004-023-01030-0
[2023] Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification
DOI: https://doi.org/10.1021/acscentsci.3c00930
[2023] Photo‐oxygenation of histidine residue inhibits α‐synuclein aggregation
DOI: https://doi.org/10.1096/fj.202301533r
[2023] Practical N-to-C peptide synthesis with minimal protecting groups
DOI: https://doi.org/10.1038/s42004-023-01030-0
[2023] Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification
DOI: https://doi.org/10.1021/acscentsci.3c00930
[2023] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin
DOI: https://doi.org/10.1016/j.pep.2023.106375
[2023] Rose Bengal Promoted Catalytic Amyloid-β Oxygenation by Sonoactivation
DOI: https://doi.org/10.1055/a-2182-7614
[2023] A chemical catalyst enabling histone acylation with endogenous acyl-CoA
DOI: https://doi.org/10.1038/s41467-023-41426-z
[2023] (Invited) Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System
DOI: https://doi.org/10.1149/ma2023-01141355mtgabs
[2023] Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins
DOI: https://doi.org/10.1021/acschemneuro.3c00264
[2023] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin
DOI: https://doi.org/10.1016/j.pep.2023.106375
[2023] Rose Bengal Promoted Catalytic Amyloid-β Oxygenation by Sonoactivation
DOI: https://doi.org/10.1055/a-2182-7614
[2023] A chemical catalyst enabling histone acylation with endogenous acyl-CoA
DOI: https://doi.org/10.1038/s41467-023-41426-z
[2023] (Invited) Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System
DOI: https://doi.org/10.1149/ma2023-01141355mtgabs
[2023] Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins
DOI: https://doi.org/10.1021/acschemneuro.3c00264
[2023] Modulation of the functional interfaces between retroviral intasomes and the human nucleosome
DOI: https://doi.org/10.1128/mbio.01083-23
[2023] Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo
DOI: https://doi.org/10.1242/bio.059783
[2023] Bioconjugation of Au 25 Nanocluster to Monoclonal Antibody at Tryptophan
DOI: https://doi.org/10.1021/acs.bioconjchem.3c00069
[2023] Attenuation of α-synuclein aggregation by catalytic photo-oxygenation
DOI: https://doi.org/10.1039/d3cc00665d
[2023] Bioconjugation of Au 25 Nanocluster to Monoclonal Antibody at Tryptophan
DOI: https://doi.org/10.1021/acs.bioconjchem.3c00069
[2023] Attenuation of α-synuclein aggregation by catalytic photo-oxygenation
DOI: https://doi.org/10.1039/d3cc00665d
[2022] Pathological complete remission of relapsed tumor by <scp>photo‐activating</scp> antibody–mimetic drug conjugate treatment
DOI: https://doi.org/10.1111/cas.15565
[2022] A Catalytic Alkylation of Ketones via sp3 C–H Bond Activation
DOI: https://doi.org/10.1021/acs.joc.2c00603
[2022] Synthesis and Astatine Labeling of a bis-iminobiotin derivative with enhanced plasma stability
DOI: https://doi.org/10.1016/s0969-8051(22)00266-9
[2022] Catalysis medicine: Participating in the chemical networks of living organisms through catalysts
DOI: https://doi.org/10.1016/j.tet.2022.133227
[2022] Sustainable and Mild Catalytic Acceptorless Dehydrogenations
DOI: https://doi.org/10.1055/a-1990-5102
[2022] Lewis Acid-Conjugated Pyrene Photoredox Catalyst Promoting the Addition Reaction of α-Silyl Amines with Benzalmalononitriles
DOI: https://doi.org/10.1248/cpb.c22-00526
[2022] A Germanium Catalyst Accelerates the Photoredox α-C(sp3)–H Alkylation of Primary Amines
DOI: https://doi.org/10.1021/acs.orglett.2c00871
[2022] Catalysis medicine: Participating in the chemical networks of living organisms through catalysts
DOI: https://doi.org/10.1016/j.tet.2022.133227
[2022] Sustainable and Mild Catalytic Acceptorless Dehydrogenations
DOI: https://doi.org/10.1055/a-1990-5102
[2022] Lewis Acid-Conjugated Pyrene Photoredox Catalyst Promoting the Addition Reaction of α-Silyl Amines with Benzalmalononitriles
DOI: https://doi.org/10.1248/cpb.c22-00526
[2022] Live Cell Synthetic Histone Acetylation by Chemical Catalyst
DOI: https://doi.org/10.1007/978-1-0716-2433-3_17
[2022] Pathological complete remission of relapsed tumor by <scp>photo‐activating</scp> antibody–mimetic drug conjugate treatment
DOI: https://doi.org/10.1111/cas.15565
[2022] Live Cell Synthetic Histone Acetylation by Chemical Catalyst
DOI: https://doi.org/10.1007/978-1-0716-2433-3_17
[2022] Linear‐Selective Allylation of Aldehydes with Simple Alkenes Mediated by Quadruple Hybrid Catalysis
DOI: https://doi.org/10.1002/adsc.202200704
[2022] Activatable iodinated BODIPYs for selective imaging and photodynamic disruption of amyloid structures in pathogenic bacterial biofilms
DOI: https://doi.org/10.1016/j.snb.2022.132475
[2022] Site-Selective α-Alkylation of 1,3-Butanediol Using a Thiophosphoric Acid Hydrogen Atom Transfer Catalyst
DOI: https://doi.org/10.1248/cpb.c22-00299
[2022] (Invited) Titanium-Catalyzed Intermolecular Radical Addition to Ketones Via Sp 3 C-H Bond Activation
DOI: https://doi.org/10.1149/ma2022-0113914mtgabs
[2022] A Catalytic Alkylation of Ketones via sp3 C–H Bond Activation
DOI: https://doi.org/10.1021/acs.joc.2c00603
[2022] Synthesis and Astatine Labeling of a bis-iminobiotin derivative with enhanced plasma stability
DOI: https://doi.org/10.1016/s0969-8051(22)00266-9
[2022] A Germanium Catalyst Accelerates the Photoredox α-C(sp3)–H Alkylation of Primary Amines
DOI: https://doi.org/10.1021/acs.orglett.2c00871
[2022] Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity
DOI: https://doi.org/10.1016/j.bbrc.2022.04.035
[2022] Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System
DOI: https://doi.org/10.1021/jacs.2c01705
[2022] Titanium(IV) Chloride-Catalyzed Photoalkylation via C(sp3)–H Bond Activation of Alkanes
DOI: https://doi.org/10.1021/acs.orglett.2c00138
[2022] Development of photo-oxygenation technology towards therapeutic strategy against Alzheimer disease
DOI: https://doi.org/10.1254/jpssuppl.95.0_1-s13-3
[2022] Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity
DOI: https://doi.org/10.1016/j.bbrc.2022.04.035
[2022] Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System
DOI: https://doi.org/10.1021/jacs.2c01705
[2022] Titanium(IV) Chloride-Catalyzed Photoalkylation via C(sp3)–H Bond Activation of Alkanes
DOI: https://doi.org/10.1021/acs.orglett.2c00138
[2022] Development of photo-oxygenation technology towards therapeutic strategy against Alzheimer disease
DOI: https://doi.org/10.1254/jpssuppl.95.0_1-s13-3
[2022] Site-Selective α-Alkylation of 1,3-Butanediol Using a Thiophosphoric Acid Hydrogen Atom Transfer Catalyst
DOI: https://doi.org/10.1248/cpb.c22-00299
[2022] Activatable iodinated BODIPYs for selective imaging and photodynamic disruption of amyloid structures in pathogenic bacterial biofilms
DOI: https://doi.org/10.1016/j.snb.2022.132475
[2022] Linear‐Selective Allylation of Aldehydes with Simple Alkenes Mediated by Quadruple Hybrid Catalysis
DOI: https://doi.org/10.1002/adsc.202200704
[2022] (Invited) Titanium-Catalyzed Intermolecular Radical Addition to Ketones Via Sp 3 C-H Bond Activation
DOI: https://doi.org/10.1149/ma2022-0113914mtgabs
[2021] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system
DOI: https://doi.org/10.1016/j.pep.2021.106043
[2021] Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound
DOI: https://doi.org/10.1016/j.jaci.2021.03.029
[2021] Catalytic photooxygenation degrades brain Aβ in vivo
DOI: https://doi.org/10.1126/sciadv.abc9750
[2021] Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer’s disease mice
DOI: https://doi.org/10.1093/brain/awab058
[2021] Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound
DOI: https://doi.org/10.1016/j.jaci.2021.03.029
[2021] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system
DOI: https://doi.org/10.1016/j.pep.2021.106043
[2021] Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer’s disease mice
DOI: https://doi.org/10.1093/brain/awab058
[2021] Live-cell epigenome manipulation by synthetic histone acetylation catalyst system
DOI: https://doi.org/10.1073/pnas.2019554118
[2021] Introduction to hybrid catalysis
DOI: https://doi.org/10.1039/d0ob90177f
[2021] A Single-Step Asymmetric Phosphodiester Synthesis from Alcohols with Phosphoenolpyruvate Phosphodiester
DOI: https://doi.org/10.1055/a-1509-9275
[2021] Data-driven catalyst optimization for stereodivergent asymmetric synthesis by iridium/boron hybrid catalysis
DOI: https://doi.org/10.1016/j.xcrp.2021.100679
[2021] Data-driven catalyst optimization for stereodivergent asymmetric synthesis by iridium/boron hybrid catalysis
DOI: https://doi.org/10.1016/j.xcrp.2021.100679
[2021] Protein Modification at Tyrosine with Iminoxyl Radicals
DOI: https://doi.org/10.1021/jacs.1c09066
[2021] Recent Progress in Chromium-Mediated Carbonyl Addition Reactions
DOI: https://doi.org/10.1055/a-1696-6429
[2021] (Invited) Catalytic Allylation of Aldehydes Using Feedstock Alkenes
DOI: https://doi.org/10.1149/ma2021-0115734mtgabs
[2021] Siloxy Esters as Traceless Activators of Carboxylic Acids: Boron‐Catalyzed Chemoselective Asymmetric Aldol Reaction**
DOI: https://doi.org/10.1002/ange.202109788
[2021] Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis
DOI: https://doi.org/10.1021/jacs.1c07060
[2021] A 4-hydroxyproline/trimethyl borate system for asymmetric synthesis of triple aldols from double aldol cyclic hemiacetals
DOI: https://doi.org/10.1016/j.tet.2021.132448
[2021] Siloxy Esters as Traceless Activators of Carboxylic Acids: Boron‐Catalyzed Chemoselective Asymmetric Aldol Reaction**
DOI: https://doi.org/10.1002/anie.202109788
[2021] Catalytic photooxygenation degrades brain Aβ in vivo
DOI: https://doi.org/10.1126/sciadv.abc9750
[2021] Live-cell epigenome manipulation by synthetic histone acetylation catalyst system
DOI: https://doi.org/10.1073/pnas.2019554118
[2021] Introduction to hybrid catalysis
DOI: https://doi.org/10.1039/d0ob90177f
[2021] Cu(I)-Catalyzed Selective Bond-Formation in the Presence of Protic Functional Groups
DOI: https://doi.org/10.5059/yukigoseikyokaishi.79.391
[2021] Protein Modification at Tyrosine with Iminoxyl Radicals
DOI: https://doi.org/10.1021/jacs.1c09066
[2021] Recent Progress in Chromium-Mediated Carbonyl Addition Reactions
DOI: https://doi.org/10.1055/a-1696-6429
[2021] Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis
DOI: https://doi.org/10.1021/jacs.1c07060
[2021] Axially Substituted Silicon Phthalocyanine Payloads for Antibody–Drug Conjugates
DOI: https://doi.org/10.1055/a-1503-6425
[2021] Axially Substituted Silicon Phthalocyanine Payloads for Antibody–Drug Conjugates
DOI: https://doi.org/10.1055/a-1503-6425
[2021] A Single-Step Asymmetric Phosphodiester Synthesis from Alcohols with Phosphoenolpyruvate Phosphodiester
DOI: https://doi.org/10.1055/a-1509-9275
[2021] A 4-hydroxyproline/trimethyl borate system for asymmetric synthesis of triple aldols from double aldol cyclic hemiacetals
DOI: https://doi.org/10.1016/j.tet.2021.132448
[2021] Siloxy Esters as Traceless Activators of Carboxylic Acids: Boron‐Catalyzed Chemoselective Asymmetric Aldol Reaction**
DOI: https://doi.org/10.1002/anie.202109788
[2021] Siloxy Esters as Traceless Activators of Carboxylic Acids: Boron‐Catalyzed Chemoselective Asymmetric Aldol Reaction**
DOI: https://doi.org/10.1002/ange.202109788
[2021] (Invited) Catalytic Allylation of Aldehydes Using Feedstock Alkenes
DOI: https://doi.org/10.1149/ma2021-0115734mtgabs
[2021] Cu(I)-Catalyzed Selective Bond-Formation in the Presence of Protic Functional Groups
DOI: https://doi.org/10.5059/yukigoseikyokaishi.79.391
[2021] Knoevenagel Condensation between 2-Methyl-thiazolo[4,5-b]pyrazines and Aldehydes
DOI: https://doi.org/10.1248/cpb.c21-00780

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