Yasunori Matsuzaki 研究室

AI 要約（直近 5 年の研究成果）

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

研究成果（9 件）

• [2026] Systematic evaluation of BBB-penetrant AAV capsids in marmosets identifies VCAP-102 as a highly efficient brain-transducing capsid
  DOI: https://doi.org/10.1016/j.omta.2026.201783
• [2025] 10246-CB-9 Preclinical Model Development for AAV-Mediated Gene Therapy in Brain Tumors
  DOI: https://doi.org/10.1093/noajnl/vdaf236.010
• [2024] Optimal different adeno-associated virus capsid/promoter combinations to target specific cell types in the common marmoset cerebral cortex
  DOI: https://doi.org/10.1016/j.omtm.2024.101337
• [2024] Improving cell-specific recombination using AAV vectors in the murine CNS by capsid and expression cassette optimization
  DOI: https://doi.org/10.1016/j.omtm.2024.101185
• [2024] Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purkinje cells
  DOI: https://doi.org/10.3389/fncel.2024.1349878
• [2023] A blood-brain barrier-penetrating AAV2 mutant created by a brain microvasculature endothelial cell-targeted AAV2 variant
  DOI: https://doi.org/10.1016/j.omtm.2023.02.016
• [2022] Protein kinase Cγ in cerebellar Purkinje cells regulates Ca ²⁺ -activated large-conductance K ⁺ channels and motor coordination
  DOI: https://doi.org/10.1073/pnas.2113336119
• [2022] Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo
  DOI: https://doi.org/10.1038/s42003-022-04200-3
• [2021] Comparative study of neuron-specific promoters in mouse brain transduced by intravenously administered AAV-PHP.eB
  DOI: https://doi.org/10.1016/j.neulet.2021.135956

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