Kazuyasu Sakaguchi 研究室

AI 要約（直近 5 年の研究成果）

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

研究成果（14 件）

• [2025] Dominant‐Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity
  DOI: https://doi.org/10.1002/cbic.202500330
• [2025] Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth
  DOI: https://doi.org/10.1038/s41419-025-07658-1
• [2025] Front Cover: Dominant‐Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity (ChemBioChem 22/2025)
  DOI: https://doi.org/10.1002/cbic.70115
• [2025] Deep learning-assisted tracking of bubble dynamics for elucidating oxygen evolution reaction on nickel electrodes
  DOI: https://doi.org/10.1016/j.jelechem.2025.119760
• [2023] Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties
  DOI: https://doi.org/10.3390/ijms242316620
• [2023] Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells
  DOI: https://doi.org/10.1242/jcs.260918
• [2023] Biomineralization through a Symmetry-Controlled Oligomeric Peptide
  DOI: https://doi.org/10.3390/biomimetics8080606
• [2023] Bilayer Hydrogel Composed of Elastin-Mimetic Polypeptides as a Bio-Actuator with Bidirectional and Reversible Bending Behaviors
  DOI: https://doi.org/10.3390/molecules28135274
• [2022] Ribosomal protein uL30 undergoes phase separation with nucleophosmin and regulates nucleolar formation in the absence of RNA
  DOI: https://doi.org/10.1016/j.bbrc.2022.12.041
• [2022] Lipid Droplet Formation Is Regulated by Ser/Thr Phosphatase PPM1D via Dephosphorylation of Perilipin 1
  DOI: https://doi.org/10.3390/ijms231912046

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所属学会・役職（0 件）

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