Yasuaki Tomioka 研究室

主宰者：Yasuaki Tomioka

岡山大学・Okayama University Hospital

AI 要約（直近 5 年の研究成果）

本研究室は、肺の移植と肺がん、胸部外傷などの胸部疾患の外科的治療を中心に研究を行っています。特に肺移植後の合併症メカニズムの解明に力を入れており、移植肺の血流異常が気道の癒合障害につながるのか、免疫抑制療法が長期的な臓器機能にどう影響するのか、といった臨床的な課題に取り組んでいます。また、血液中の特定の物質が移植後の肺機能低下の予測指標となるかどうかを調べるなど、バイオマーカーを活用した診断法の開発も進めています。一方、肺がんや胸壁肉腫などの悪性腫瘍に対しては、外科的切除と薬物療法の組み合わせ方の最適化を検討しており、患者背景に応じた治療選択の指針を提供することを目指しています。さらに、胸部外傷時の肋骨骨折固定術や、縦隔感染症などの救急疾患に対しても、低侵襲な内視鏡手術やロボット支援手術などの最新の手術技術を活用して、患者の負担軽減と予後改善を実現する方法を模索しています。これらの研究を通じて、より安全で有効な胸部外科治療の確立に貢献することが研究室の目標です。

※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。

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研究成果（51 件）

[2026] An Atypical Surgical Case of Lung Cancer With Unilateral Absence of the Pulmonary Artery, With Only the Superior Branch Remaining
DOI: https://doi.org/10.1002/rcr2.70554
[2026] Survival outcomes of patients with uncommon EGFR mutations in surgically resected lung adenocarcinoma: A multi-institutional real-world database study (CReGYT-01 EGFR study)
DOI: https://doi.org/10.1016/j.lungcan.2026.108908
[2026] Lung Segmental Perfusion Defect Is Associated With Airway Complications After Living-Donor Lobar Lung Transplantation
DOI: https://doi.org/10.1093/icvts/ivag139
[2025] Novel pulmonary abdominal normothermic regional perfusion circuit for simultaneous in-donor evaluation and preservation of lungs and abdominal organs in donation after circulatory death
DOI: https://doi.org/10.1007/s11748-025-02137-y
[2025] Nightmare case of repeated hemorrhagic pancreatitis due to pancreatic head cancer in the acute stage after two-stage lung transplantation
DOI: https://doi.org/10.1016/j.jhlto.2025.100245
[2025] Single-cell and spatial transcriptomic characterization of pulmonary pleomorphic carcinoma
DOI: https://doi.org/10.1038/s42003-025-09162-w
[2025] Effect of Donor-Recipient Age Difference on Living-Donor Lung Transplantation Outcomes
DOI: https://doi.org/10.1093/ejcts/ezaf446
[2025] Downward hyperinflation of the native lung after right single lung transplantation for COPD: A case report highlighting diaphragmatic mobility
DOI: https://doi.org/10.1016/j.jhlto.2025.100268
[2025] Similar Trend in Benefit of Adjuvant Platinum in Lung Cancer Patients Irrespective of Epidermal Growth Factor Receptor Mutation Status
DOI: https://doi.org/10.1093/ejcts/ezaf239
[2025] Recurrent diffuse panbronchiolitis after lung transplantation: Off-label use of inhaled tobramycin for Pseudomonas aeruginosa control in a transplant recipient
DOI: https://doi.org/10.1016/j.ijid.2025.107913

続きを表示（残り 41 件）

[2025] Primary chest wall sarcoma: advances in surgical management and outcomes
DOI: https://doi.org/10.1007/s00590-025-04260-1
[2024] P1.08C.05 The Clinicopathological and Prognostic Significance of Skip-N2 Metastases: A Retrospective Multicenter Study
DOI: https://doi.org/10.1016/j.jtho.2024.09.331
[2024] Impact of central nervous system metastasis after complete resection of lung adenocarcinomas harboring common EGFR mutation – A real-world database study in Japan: The CReGYT-01 EGFR study
DOI: https://doi.org/10.1016/j.ejca.2024.113951
[2024] Pulmonary ligament rupture due to a bronchial artery aneurysm-induced hematoma: a case report
DOI: https://doi.org/10.1186/s40792-024-01810-3
[2024] Long-term outcomes of lung transplantation requiring renal replacement therapy: A single-center experience
DOI: https://doi.org/10.1016/j.resinv.2024.01.001
[2024] Plasma concentrations of histidine-rich glycoprotein in primary graft dysfunction after lung transplantation
DOI: https://doi.org/10.1093/icvts/ivae021
[2024] Prognostic Analysis of Pathological Stage I Lung Adenocarcinoma Harboring Major EGFR Mutations
DOI: https://doi.org/10.1016/j.cllc.2024.12.011
[2024] [A Review of 70 Cases of Thoracic Trauma with Rib Fixation:Indications and Practical Innovations of the Procedure].
[2024] Successful Treatment of Descending Necrotizing Mediastinitis by Thoracotomy Using a Pedicled Omental Flap: A Case Report
DOI: https://doi.org/10.7759/cureus.75211
[2024] Sufficient treatment of lower posterior localized descending necrotizing mediastinitis with initial cervical drainage and additional thoracoscopic drainage: A case study on the efficacy of a localized approach
DOI: https://doi.org/10.2995/jacsurg.38.585
[2024] Identification of Tumor-suppressive MicroRNAs and Their Targets Oncogenes in Small Cell Lung Cancer
DOI: https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4934
[2023] Elderly lung transplant recipients show acceptable long-term outcomes for lung transplantation: A propensity score-matched analysis
DOI: https://doi.org/10.1007/s00595-023-02699-5
[2023] Successful Living-donor Lobar Lung Transplantation With BK Virus-related Hemorrhagic Cystitis Throughout the Perioperative Period
DOI: https://doi.org/10.1097/txd.0000000000001556
[2023] Comment on: “Randomized Controlled Trial of Surgical Rib Fixation to Nonoperative Management in Severe Chest Wall Injury”
DOI: https://doi.org/10.1097/as9.0000000000000360
[2023] In vivo lung perfusion for prompt recovery from primary graft dysfunction after lung transplantation
DOI: https://doi.org/10.1016/j.healun.2023.10.011
[2023] Successful management of temporary veno-venous extracorporeal membrane oxygenation for a pediatric lung transplant recipient with bronchiolitis obliterans syndrome awaiting lung re-transplantation: a case report
DOI: https://doi.org/10.1186/s40792-023-01742-4
[2023] Robot-assisted thoracoscopic right upper lobectomy with displaced B3 and absence of minor fissure: a case report
DOI: https://doi.org/10.1007/s00276-023-03197-6
[2023] Intraoperative video of combined spinal endoscopy and robot-assisted resection for dumbbell tumors.
DOI: https://doi.org/10.21037/asvide.2023.115
[2023] Combined minimally invasive surgery for a dumbbell tumor using spinal endoscopy and robot-assisted intrathoracic surgery: a case report
DOI: https://doi.org/10.21037/vats-22-61
[2023] Identification of genetic loci associated with renal dysfunction after lung transplantation using an ethnic-specific single-nucleotide polymorphism array
DOI: https://doi.org/10.1038/s41598-023-36143-y
[2023] Diagnostic value of circulating microRNA-21 in chronic lung allograft dysfunction after bilateral cadaveric and living-donor lobar lung transplantation
DOI: https://doi.org/10.1016/j.heliyon.2023.e14903
[2022] Acute Pulmonary Edema Due to Arteriovenous Shunt Placement After Lung Transplantation
DOI: https://doi.org/10.1016/j.athoracsur.2021.12.017
[2022] The impact of prognostic nutrition index on the waitlist mortality of lung transplantation
DOI: https://doi.org/10.1007/s11748-022-01895-3
[2022] Current status of inhaled nitric oxide therapy for lung transplantation in Japan: A nationwide survey
DOI: https://doi.org/10.2995/jacsurg.36.722
[2022] Survival and prognostic factors in patients undergoing pulmonary metastasectomy for lung metastases from retroperitoneal sarcoma
DOI: https://doi.org/10.1186/s12957-022-02552-y
[2022] Identification of Single-Nucleotide Polymorphisms Associated with Renal Dysfunction After Lung Transplantation Using Ethnic-Specific SNP Array
DOI: https://doi.org/10.1016/j.healun.2022.01.623
[2022] Diagnostic Value of Circulating Microrna-21 in Chronic Lung Allograft Dysfunction after Bilateral Cadaveric and Living-Donor Lobar Lung Transplantation
DOI: https://doi.org/10.2139/ssrn.4268760
[2022] Paediatric lung transplantation: the impact of age on the survival
DOI: https://doi.org/10.1007/s00595-022-02492-w
[2021] Effect of preoperative long-term use of corticosteroids on the development of post-transplant lymphoproliferative disorders after lung transplantation: a single-center experience in Japan
DOI: https://doi.org/10.1007/s00595-021-02390-7
[2021] Risk Assessment of Chronic Lung Allograft Dysfunction Phenotypes after Living-Donor Lobar Lung Transplantation According to the 2019 ISHLT Classification System
DOI: https://doi.org/10.1016/j.healun.2021.01.867
[2021] Pediatric Lung Transplantation−Intermediate Outcomes of a Japanese Center
DOI: https://doi.org/10.1016/j.healun.2021.01.995
[2021] Post-Transplant Lymphoproliferative Disorder in Lung Transplantation: A Single-Center Experience in Japan
DOI: https://doi.org/10.1016/j.healun.2021.01.884
[2021] The UNCX Polymorphism is Associated with the Development of Renal Dysfunction after Lung Transplantation
DOI: https://doi.org/10.1016/j.healun.2021.01.977
[2021] Combination of Neutrophil to Lymphocyte Ratio and Glasgow Prognostic Score Improves Prognostic Accuracy in Lung Transplantation: Validation of 9 Preoperative Prognostic Scoring Methods
DOI: https://doi.org/10.1016/j.healun.2021.01.1007
[2021] Plasma Levels of Histidine-Rich Glycoprotein are Associated with the Development of Primary Graft Dysfunction after Lung Transplantation
DOI: https://doi.org/10.1016/j.healun.2021.01.455
[2021] The prognostic impact of sarcopenia on elderly patients undergoing pulmonary resection for non-small cell lung cancer
DOI: https://doi.org/10.1007/s00595-020-02221-1
[2021] Long-term Follow-up of Living-Donor Kidney Transplantation after Cadaveric Lung Transplantation.
DOI: https://doi.org/10.18926/amo/61439
[2021] Successful Bronchoscopic Treatment for Postoperative Bronchopleural Fistula Using N-butyl-2-cyanoacrylate (NBCA): Report of a Post-completion Pneumonectomy Case with a History of Induction Chemoradiotherapy Followed by Bilobectomy for Advanced Lung Cancer.
DOI: https://doi.org/10.18926/amo/61440
[2021] Lung transplantation for idiopathic multicentric Castleman disease: potential efficacy and tolerability of a humanized anti-interleukin-6 receptor monoclonal antibody
DOI: https://doi.org/10.1186/s40792-021-01297-2
[2021] Lung Transplantation for Bronchiectasis Due to Hyperimmunoglobulin E Syndrome
DOI: https://doi.org/10.1016/j.athoracsur.2021.05.088
[2021] Current status of inhaled nitric oxide therapy for lung transplantation in Japan: a nationwide survey
DOI: https://doi.org/10.1007/s11748-021-01648-8

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AI 要約（直近 5 年の研究成果）

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関連研究室(8 件)

研究成果（51 件）

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