Tomoyoshi Soga 研究室
主宰者：Tomoyoshi Soga
慶應義塾大学・Keio University Hospital
AI 要約（直近 5 年の研究成果）
Soga研究室は、生体内の小分子物質（代謝産物）を網羅的に測定・分析する代謝学（メタボロミクス）を用いて、疾病の仕組みを理解し、治療法の開発につなげる研究を行っています。特に、最新の分析機器を活用して、血液や唾液、組織などから多くの代謝産物を同時に検出し、それらの変化がどの生物学的経路に関連しているかを解き明かすことに力を入れています。例えば、がんや炎症性腸疾患、肥満といった様々な疾患で、患者の代謝産物がどのように変化しているかを調べ、病気の本質に迫る研究を展開しています。
また、この研究室では単なる代謝産物の測定にとどまらず、複数のオミクス情報（遺伝子発現やタンパク質など）を組み合わせて、生体内で起きている複雑な代謝の変化を総合的に理解しようとしています。腫瘍微小環境の免疫細胞の動向、老化に伴う細胞の異常、腎臓病と腸内細菌の関連性といった、多岐にわたるテーマを手がけています。これらの研究を通じて、現在の治療に効きにくい患者さんに対する新しい治療戦略を提案することを目指しており、基礎研究から臨床応用までを幅広くカバーする分野です。
※ AI（Claude）が、公開されている論文要旨から研究の問い・手法・主要な発見を事実情報として抽出・再構成して自動生成しています。誤りを含む可能性があるため、正確性は研究室公式情報でご確認ください。
外部リンク
関連研究室(8 件)
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